ARG10080

anti-Staphylococcus Enterotoxin B antibody [SEB]

anti-Staphylococcus Enterotoxin B antibody [SEB] for ELISA and Staphylococcus aureus

Microbiology and Infectious Disease antibody

Overview

Product Description Mouse Monoclonal antibody [SEB] recognizes Staphylococcus Enterotoxin B
Tested Reactivity S. aureus
Tested Application ELISA
Host Mouse
Clonality Monoclonal
Clone SEB
Isotype IgG1,k
Target Name Staphylococcus Enterotoxin B
Antigen Species Bacteria
Immunogen SEB purified from Staphylococcus aureus
Conjugation Un-conjugated

Application Instructions

Application Note * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

Properties

Form Liquid
Purification Protein G affinity purified
Buffer 0.01M PBS (pH 7.2)
Concentration 1 mg/ml
Storage instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Background Staphylococcal enterotoxin B (SEB) is an enterotoxin secreted by Staphylococcus aureus. The bacterium thrives on meet, baking and dairy products and also colonizes in host nasal passageway. Ingestion of SEB contaminated food is the common cause of “food poisoning”, manifested by flu-like symptoms, vomiting, diarrhea and intestinal cramps. In severe cases, SEB can cause respiratory failure and systemic toxic shock. These symptoms are the results of increased membrane permeability and abnormal activation of T-lymphocytes by SEB. SEB acts as a superantigen by binding directly to major histocompatibility complex class II (MHCII) on antigen presenting cells, thus, causing massive CD4 and CD8 T-cells activation and cytokine production. If unchecked, the process can result in systemic organ failure and death.
Resrarch Area Microbiology and Infectious Disease antibody