anti-Synaptotagmin 1 antibody

anti-Synaptotagmin 1 antibody for Western blot and Rat

Cancer antibody; Metabolism antibody; Neuroscience antibody; Signaling Transduction antibody


Product Description Rabbit Polyclonal antibody recognizes Synaptotagmin 1
Tested Reactivity Rat
Predict Reactivity Hu, Ms, Bov, Chk, NHuPrm
Tested Application WB
Host Rabbit
Clonality Polyclonal
Isotype IgG
Target Name Synaptotagmin 1
Antigen Species Rat
Immunogen Synthetic peptide corresponding to amino acid residues specific to synaptotagmin 1 conjugated to KLH
Conjugation Un-conjugated
Alternate Names P65; Synaptotagmin I; SytI; SVP65; SYT; p65; Synaptotagmin-1

Application Instructions

Application Suggestion
Tested Application Dilution
Application Note Specific for ~65k synaptotagmin I protein.
* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.


Form Liquid
Purification Affinity Purified
Buffer 10 mM HEPES (pH 7.5), 150 mM NaCl, 0.1 mg/ml BSA and 50% Glycerol
Stabilizer 0.1 mg/ml BSA, 50% Glycerol
Storage Instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.


Database Links

GeneID: 25716 Rat SYT1

Swiss-port # P21707 Rat Synaptotagmin-1

Gene Symbol SYT1
Gene Full Name synaptotagmin I
Background Synaptotagmin 1 is a synaptic vesicle membrane glycoprotein that is widely expressed throughout the CNS and is generally thought to act as the Ca2+ sensor in the regulation of exocytosis and neurotransmitter release (Littleton and Bellen 1995). Recent studies indicate that synaptotagmin’s Ca2+ mediated binding of SNAP25 is essential for the Ca2+ dependent triggering of membrane fusion (Zhang et al., 2002). It has recently been demonstrated that discrete residues within the c(2)b binding domain of synaptotagmin 1 independently specify endocytic rate and synaptic vesicle size (Poskanzer et al., 2006).
Research Area Cancer antibody; Metabolism antibody; Neuroscience antibody; Signaling Transduction antibody
Calculated MW 48 kDa

Images (1) Click the Picture to Zoom In

  • ARG52436 anti-Synaptotagmin 1 antibody WB image

    Western blot: Rat cortex lysate showing specific labeling of the ~65k synaptotagmin protein stained with ARG52436 anti-Synaptotagmin 1 antibody.