ARG45787
anti-Syntaxin 12 / Syntaxin-13 antibody
anti-Syntaxin 12 / Syntaxin-13 antibody for Flow cytometry,ICC/IF,Western blot and Human,Mouse,Rat
Overview
Product Description | Rabbit Polyclonal antibody recognizes Syntaxin 12 / Syntaxin-13 |
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Tested Reactivity | Hu, Ms, Rat |
Tested Application | FACS, ICC/IF, WB |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | IgG |
Target Name | Syntaxin 12 / Syntaxin-13 |
Antigen Species | Human |
Immunogen | Recombinant protein containing to human Syntaxin 12 / Syntaxin-13. |
Conjugation | Un-conjugated |
Alternate Names | STX12; Syntaxin 12; STX13; STX14; Syntaxin-12 |
Application Instructions
Application Suggestion |
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Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||||
Observed Size | 37 kDa |
Properties
Form | Liquid |
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Purification | Affinity purified |
Buffer | 0.2% Na2HPO4, 0.9% NaCl and 4% Trehalose. |
Stabilizer | 4% Trehalose |
Concentration | 0.5 mg/ml |
Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
Database Links | |
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Gene Symbol | STX12 |
Gene Full Name | Syntaxin 12 |
Background | Predicted to enable SNAP receptor activity and SNARE binding activity. Involved in autophagosome assembly; cholesterol efflux; and protein stabilization. Located in several cellular components, including BLOC-1 complex; phagocytic vesicle; and phagophore assembly site. Part of SNARE complex. [provided by Alliance of Genome Resources, Feb 2025] |
Function | SNARE promoting fusion of transport vesicles with target membranes. Together with SNARE STX6, promotes movement of vesicles from endosomes to the cell membrane, and may therefore function in the endocytic recycling pathway. Through complex formation with GRIP1, GRIA2 and NSG1 controls the intracellular fate of AMPAR and the endosomal sorting of the GRIA2 subunit toward recycling and membrane targeting. [UniProt] |
Cellular Localization | Endosome; Golgi apparatus; Membrane. [UniProt] |
Calculated MW | 32 kDa |
PTM | Acetylation; Phosphoprotein. [UniProt] |
Images (5) Click the Picture to Zoom In
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ARG45787 anti-Syntaxin 12 / Syntaxin-13 antibody ICC/IF image
Immunofluorescence: Hela stained with ARG45787 anti-Syntaxin 12 / Syntaxin-13 antibody at 5 μg/ml dilution.
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ARG45787 anti-Syntaxin 12 / Syntaxin-13 antibody WB image
Western blot: MDA-MB-453 and 293T stained with ARG45787 anti-Syntaxin 12 / Syntaxin-13 antibody at 0.5 μg/ml dilution.
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ARG45787 anti-Syntaxin 12 / Syntaxin-13 antibody FACS image
Flow Cytometry: 293T stained with ARG45787 anti-Syntaxin 12 / Syntaxin-13 antibody at 1 µg/10^6 cells dilution.
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ARG45787 anti-Syntaxin 12 / Syntaxin-13 antibody WB image
Western blot: Rat brain stained with ARG45787 anti-Syntaxin 12 / Syntaxin-13 antibody at 0.5 μg/ml dilution.
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ARG45787 anti-Syntaxin 12 / Syntaxin-13 antibody WB image
Western blot: Mouse brain stained with ARG45787 anti-Syntaxin 12 / Syntaxin-13 antibody at 0.5 μg/ml dilution.