ARG45634
anti-TMBIM1 antibody
anti-TMBIM1 antibody for Flow cytometry,IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Mouse,Rat
Overview
| Product Description | Rabbit Polyclonal antibody recognizes TMBIM1 |
|---|---|
| Tested Reactivity | Hu, Ms, Rat |
| Tested Application | FACS, IHC-P, WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | TMBIM1 |
| Antigen Species | Human |
| Immunogen | Synthetic peptide corresponding to N-terminal region of human TMBIM1. |
| Conjugation | Un-conjugated |
| Alternate Names | TMBIM1; Transmembrane BAX Inhibitor Motif Containing 1; RECS1; LFG3; PP1201; Transmembrane BAX Inhibitor Motif-Containing Protein 1; Protein Lifeguard 3; Protein RECS1 Homolog; MSTP100; MST100 |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||||
| Observed Size | 35 kDa |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purified |
| Buffer | 0.9% NaCl, 0.2% Na2HPO4, 0.01% Sodium azide and 4% Trehalose. |
| Preservative | 0.01% Sodium azide |
| Stabilizer | 4% Trehalose |
| Concentration | 0.5 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | TMBIM1 |
| Gene Full Name | Transmembrane BAX Inhibitor Motif Containing 1 |
| Background | Enables death receptor binding activity. Involved in negative regulation of Fas signaling pathway; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors; and negative regulation of protein localization to plasma membrane. Located in Golgi membrane; endosome membrane; and lysosomal membrane. [provided by Alliance of Genome Resources, Feb 2025] |
| Function | Negatively regulates aortic matrix metalloproteinase-9 (MMP9) production and may play a protective role in vascular remodeling. [UniProt] |
| Cellular Localization | Endosome; Lysosome; Membrane. [UniProt] |
| Calculated MW | 35 kDa |
| PTM | Phosphoprotein. [UniProt] |
Images (5) Click the Picture to Zoom In
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ARG45634 anti-TMBIM1 antibody IHC-P image
Immunohistochemistry: Human gastric cancer stained with ARG45634 anti-TMBIM1 antibody at 2 μg/ml dilution.
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ARG45634 anti-TMBIM1 antibody WB image
Western blot: HepG2 stained with ARG45634 anti-TMBIM1 antibody at 0.5 μg/ml dilution.
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ARG45634 anti-TMBIM1 antibody FACS image
Flow Cytometry: HepG2 stained with ARG45634 anti-TMBIM1 antibody at 1 µg/10^6 cells dilution.
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ARG45634 anti-TMBIM1 antibody WB image
Western blot: Rat liver stained with ARG45634 anti-TMBIM1 antibody at 0.5 μg/ml dilution.
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ARG45634 anti-TMBIM1 antibody WB image
Western blot: Mouse kidney stained with ARG45634 anti-TMBIM1 antibody at 0.5 μg/ml dilution.
