ARG45253
anti-TMC7 antibody
anti-TMC7 antibody for Flow cytometry,IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Mouse,Rat
Overview
| Product Description | Polyclonal antibody recognizes TMC7 |
|---|---|
| Tested Reactivity | Hu, Ms, Rat |
| Tested Application | FACS, IHC-P, WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | TMC7 |
| Antigen Species | Human |
| Immunogen | Recombinant protein containing to human TMC7. |
| Conjugation | Un-conjugated |
| Alternate Names | TMC7; Transmembrane Channel Like 7; Transmembrane Channel-Like Protein 7; FLJ21240 |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||||
| Observed Size | 90 kDa |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purification with immunogen. |
| Buffer | 0.2% Na2HPO4, 0.9% NaCl and 4% Trehalose. |
| Stabilizer | 4% Trehalose |
| Concentration | 0.5 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links |
Swiss-port # Q7Z402 Human Transmembrane channel-like protein 7 Swiss-port # Q8C428 Mouse Transmembrane channel-like protein 7 |
|---|---|
| Gene Symbol | TMC7 |
| Gene Full Name | Transmembrane Channel Like 7 |
| Background | Predicted to enable ion channel inhibitor activity and mechanosensitive monoatomic ion channel activity. Predicted to be involved in sensory perception of mechanical stimulus. Predicted to be located in plasma membrane. Predicted to be active in neuronal cell body. [provided by Alliance of Genome Resources, Nov 2024] |
| Function | Acts as an inhibitory modulator of PIEZO2 mechanosensitive channel in dorsal root ganglion (DRG) neurons through physical interactions or interference with the interaction between PIEZO2 and the cytoskeleton.. [UniProt] |
| Cellular Localization | Membrane. [UniProt] |
| Calculated MW | 86 kDa |
| PTM | Glycoprotein ; Phosphoprotein. [UniProt] |
Images (5) Click the Picture to Zoom In
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ARG45253 anti-TMC7 antibody IHC-P image
Immunohistochemistry: Human colorectal adenocarcinoma stained with ARG45253 anti-TMC7 antibody at 2 μg/ml dilution.
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ARG45253 anti-TMC7 antibody WB image
Western blot: HepG2 and U-87MG stained with ARG45253 anti-TMC7 antibody at 0.5 μg/ml dilution.
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ARG45253 anti-TMC7 antibody FACS image
Flow Cytometry: SiHa stained with ARG45253 anti-TMC7 antibody at 1 µg/10^6 cells dilution.
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ARG45253 anti-TMC7 antibody WB image
Western blot: Rat testis and C6 stained with ARG45253 anti-TMC7 antibody at 0.5 μg/ml dilution.
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ARG45253 anti-TMC7 antibody WB image
Western blot: RAW264.7 stained with ARG45253 anti-TMC7 antibody at 0.5 μg/ml dilution.
