ARG46595
anti-TMIGD2 / IGPR1 antibody
anti-TMIGD2 / IGPR1 antibody for Western blot,IHC-Formalin-fixed paraffin-embedded sections and Human
Overview
| Product Description | Rabbit Polyclonal antibody recognizes TMIGD2 / IGPR1 |
|---|---|
| Tested Reactivity | Hu |
| Tested Application | IHC-P, WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | TMIGD2 / IGPR1 |
| Antigen Species | Human |
| Immunogen | A 18 amino acid synthetic peptide within the last 50 amino acids of human TMIGD2 / IGPR1. |
| Conjugation | Un-conjugated |
| Alternate Names | transmembrane and immunoglobulin domain containing 2; TMIGD2; IGPR1; IGPR-1; IGPR1; UNQ3059/PRO9879; Transmembrane and immunoglobulin domain-containing protein 2; Immunoglobulin and proline-rich receptor 1 |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||
| Observed Size | 31 kDa |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity chromatography purified |
| Buffer | PBS and 0.02% Sodium azide. |
| Preservative | 0.02% Sodium azide |
| Concentration | 1 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -645°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links |
Swiss-port # Q96BF3 Human Transmembrane and immunoglobulin domain-containing protein 2 |
|---|---|
| Gene Symbol | TMIGD2 |
| Gene Full Name | transmembrane and immunoglobulin domain containing 2 |
| Background | Enables coreceptor activity. Involved in positive regulation of T cell activation; positive regulation of angiogenesis; and positive regulation of cytokine production. Predicted to be located in plasma membrane. Predicted to be active in neuron projection. [provided by Alliance of Genome Resources, Jul 2025] |
| Function | Plays a role in cell-cell interaction, cell migration, and angiogenesis. Through interaction with HHLA2, costimulates T-cells in the context of TCR-mediated activation. Enhances T-cell proliferation and cytokine production via an AKT-dependent signaling cascade. [UniProt] |
| Cellular Localization | Cell membrane; Cell membrane . [UniProt] |
| Calculated MW | 31 kDa |
| PTM | Phosphoprotein; Disulfide bond; Glycoprotein. [UniProt] |
