ARG46597
anti-TMPRSS2 antibody
anti-TMPRSS2 antibody for Western blot and Human,Mouse,Rat
Overview
| Product Description | Rabbit Polyclonal antibody recognizes TMPRSS2 |
|---|---|
| Tested Reactivity | Hu, Ms, Rat |
| Tested Application | WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | TMPRSS2 |
| Antigen Species | Human |
| Immunogen | A 12 amino acid synthetic peptide within the last 50 amino acids of human TMPRSS2. |
| Conjugation | Un-conjugated |
| Alternate Names | TMPRSS2; Serine protease 10; PRSS10; PP9284; EC 3.4.21.-; Transmembrane protease serine 2 |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||
| Observed Size | 54 kDa |
Properties
| Purification | Affinity chromatography purified |
|---|---|
| Buffer | PBS and 0.02% Sodium azide. |
| Preservative | 0.02% Sodium azide |
| Concentration | 1 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | TMPRSS2 |
| Gene Full Name | transmembrane serine protease 2 |
| Background | This gene encodes a protein that belongs to the serine protease family. The encoded protein contains a type II transmembrane domain, a receptor class A domain, a scavenger receptor cysteine-rich domain and a protease domain. Serine proteases are known to be involved in many physiological and pathological processes. This gene was demonstrated to be up-regulated by androgenic hormones in prostate cancer cells and down-regulated in androgen-independent prostate cancer tissue. The protease domain of this protein is thought to be cleaved and secreted into cell media after autocleavage. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2008] |
| Calculated MW | 54 kDa |
| PTM | Proteolytically processed; by an autocatalytic mechanism. |
Images (2) Click the Picture to Zoom In
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ARG46597 anti-TMPRSS2 antibody ICC/IF image
Immunofluorescence: A549 stained with ARG46597 anti-TMPRSS2 antibody.
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ARG46597 anti-TMPRSS2 antibody WB image
Western blot: Rat Tissues stained with ARG46597 anti-TMPRSS2 antibody.
