ARG46601
anti-TOPAZ1 antibody
anti-TOPAZ1 antibody for Western blot,IHC-Formalin-fixed paraffin-embedded sections and Human,Mouse,Rat
Overview
| Product Description | Rabbit Polyclonal antibody recognizes TOPAZ1 |
|---|---|
| Tested Reactivity | Hu, Ms, Rat |
| Tested Application | IHC-P, WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | TOPAZ1 |
| Antigen Species | Human |
| Immunogen | A 19 amino acid synthetic peptide within the last 50 amino acids of human TOPAZ1. |
| Conjugation | Un-conjugated |
| Alternate Names | testis and ovary specific PAZ domain containing 1; TOPAZ1; C3orf77; C3orf77; Testis- and ovary-specific PAZ domain-containing protein 1 |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||
| Observed Size | 60,240 kDa |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity chromatography purified |
| Buffer | PBS and 0.02% Sodium azide. |
| Preservative | 0.02% Sodium azide |
| Concentration | 1 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -651°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links |
Swiss-port # E5FYH1 Mouse Testis- and ovary-specific PAZ domain-containing protein 1 Swiss-port # Q8N9V7 Human Testis- and ovary-specific PAZ domain-containing protein 1 |
|---|---|
| Gene Symbol | TOPAZ1 |
| Gene Full Name | testis and ovary specific PAZ domain containing 1 |
| Background | Predicted to be involved in spermatocyte division. Predicted to act upstream of or within apoptotic process; ectopic germ cell programmed cell death; and lncRNA transcription. Predicted to be located in cytosol. [provided by Alliance of Genome Resources, Jul 2025] |
| Function | Important for normal spermatogenesis and male fertility. Specifically required for progression to the post-meiotic stages of spermatocyte development. Seems to be necessary for normal expression levels of a number of testis-expressed gene transcripts, although its role in this process is unclear. [UniProt] |
| Cellular Localization | Cytoplasm; Cytosol. [UniProt] |
| Calculated MW | 65, 186 kDa |
