ARG45430
anti-TRAP alpha / TRAPA antibody
anti-TRAP alpha / TRAPA antibody for Flow cytometry,ICC/IF,IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Monkey,Mouse,Rat
Overview
| Product Description | Rabbit Polyclonal antibody recognizes TRAP alpha / TRAPA |
|---|---|
| Tested Reactivity | Hu, Ms, Rat, Mk |
| Tested Application | FACS, ICC/IF, IHC-P, WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | TRAP alpha / TRAPA |
| Antigen Species | Human |
| Immunogen | Recombinant protein containing to human TRAP alpha/TRAPA. |
| Conjugation | Un-conjugated |
| Alternate Names | SSR1; Signal Sequence Receptor Subunit 1; TRAPA; Translocon-Associated Protein Subunit Alpha; Signal Sequence Receptor Subunit Alpha; Signal Sequence Receptor, Alpha; SSR-Alpha; Translocon-Associated Protein Alpha Subunit; Translocon-Associated Protein Alpha; SSR Alpha Subunit; TRAP Alpha; TRAP-Alpha |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||||||
| Observed Size | 36 kDa |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purified |
| Buffer | 0.2% Na2HPO4, 0.9% NaCl and 4% Trehalose. |
| Stabilizer | 4% Trehalose |
| Concentration | 0.5 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links |
Swiss-port # P43307 Human Translocon-associated protein subunit alpha Swiss-port # Q9CY50 Mouse Translocon-associated protein subunit alpha |
|---|---|
| Gene Symbol | SSR1 |
| Gene Full Name | Signal Sequence Receptor Subunit 1 |
| Background | The signal sequence receptor (SSR) is a glycosylated endoplasmic reticulum (ER) membrane receptor associated with protein translocation across the ER membrane. The SSR consists of 2 subunits, a 34-kD glycoprotein encoded by this gene and a 22-kD glycoprotein. This gene generates several mRNA species as a result of complex alternative polyadenylation. This gene is unusual in that it utilizes arrays of polyA signal sequences that are mostly non-canonical. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2014] |
| Function | TRAP proteins are part of a complex whose function is to bind calcium to the ER membrane and thereby regulate the retention of ER resident proteins. May be involved in the recycling of the translocation apparatus after completion of the translocation process or may function as a membrane-bound chaperone facilitating folding of translocated proteins. [UniProt] |
| Cellular Localization | Endoplasmic reticulum; Membrane. [UniProt] |
| Calculated MW | 32 kDa |
| PTM | Glycoprotein; Phosphoprotein. [UniProt] |
Images (9) Click the Picture to Zoom In
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ARG45430 anti-TRAP alpha / TRAPA antibody IHC-P image
Immunohistochemistry: Human liver cancer stained with ARG45430 anti-TRAP alpha / TRAPA antibody at 2 μg/ml dilution.
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ARG45430 anti-TRAP alpha / TRAPA antibody ICC/IF image
Immunofluorescence: U2OS stained with ARG45430 anti-TRAP alpha / TRAPA antibody at 5 μg/ml dilution.
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ARG45430 anti-TRAP alpha / TRAPA antibody WB image
Western blot: A431 and HL-60 stained with ARG45430 anti-TRAP alpha / TRAPA antibody at 0.5 μg/ml dilution.
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ARG45430 anti-TRAP alpha / TRAPA antibody FACS image
Flow Cytometry: K562 stained with ARG45430 anti-TRAP alpha / TRAPA antibody at 1 µg/10^6 cells dilution.
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ARG45430 anti-TRAP alpha / TRAPA antibody IHC-P image
Immunohistochemistry: Rat brain stained with ARG45430 anti-TRAP alpha / TRAPA antibody at 2 μg/ml dilution.
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ARG45430 anti-TRAP alpha / TRAPA antibody WB image
Western blot: Rat liver stained with ARG45430 anti-TRAP alpha / TRAPA antibody at 0.5 μg/ml dilution.
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ARG45430 anti-TRAP alpha / TRAPA antibody IHC-P image
Immunohistochemistry: Mouse brain stained with ARG45430 anti-TRAP alpha / TRAPA antibody at 2 μg/ml dilution.
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ARG45430 anti-TRAP alpha / TRAPA antibody WB image
Western blot: Mouse liver stained with ARG45430 anti-TRAP alpha / TRAPA antibody at 0.5 μg/ml dilution.
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ARG45430 anti-TRAP alpha / TRAPA antibody WB image
Western blot: COS-7 stained with ARG45430 anti-TRAP alpha / TRAPA antibody at 0.5 μg/ml dilution.
