ARG22233
anti-TRPC7 antibody [S64A-36]
anti-TRPC7 antibody [S64A-36] for ICC/IF,IHC-Formalin-fixed paraffin-embedded sections,Immunoprecipitation,Western blot and Human,Mouse,Rat
Overview
| Product Description | Mouse Monoclonal antibody [S64A-36] recognizes TRPC7 |
|---|---|
| Tested Reactivity | Hu, Ms, Rat |
| Tested Application | ICC/IF, IHC-P, IP, WB |
| Specificity | Detects ~100kDa. |
| Host | Mouse |
| Clonality | Monoclonal |
| Clone | S64A-36 |
| Isotype | IgG1 |
| Target Name | TRPC7 |
| Antigen Species | Human |
| Immunogen | Synthetic peptide around aa. 845-862 of Human TrpC7 |
| Conjugation | Un-conjugated |
| Alternate Names | hTRP7; Transient receptor protein 7; TrpC7; Short transient receptor potential channel 7; TRP-7; TRP7 |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Purification with Protein G. |
| Buffer | PBS (pH 7.4), 0.09% Sodium azide and 50% Glycerol |
| Preservative | 0.09% Sodium azide |
| Stabilizer | 50% Glycerol |
| Concentration | 1 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links |
Swiss-port # Q9HCX4 Human Short transient receptor potential channel 7 Swiss-port # Q9WVC5 Mouse Short transient receptor potential channel 7 |
|---|---|
| Gene Symbol | TRPC7 |
| Gene Full Name | transient receptor potential cation channel, subfamily C, member 7 |
| Function | Thought to form a receptor-activated non-selective calcium permeant cation channel. Probably is operated by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases or G-protein coupled receptors. Activated by diacylglycerol (DAG) (By similarity). May also be activated by intracellular calcium store depletion. [UniProt] |
| Cellular Localization | Membrane |
| Calculated MW | 100 kDa |
| PTM | Phosphorylation by PRKG1 at Thr-15 negatively regulates TRPC7 activity. |
Images (1) Click the Picture to Zoom In
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ARG22233 anti-TRPC7 antibody [S64A-36] WB image
Western blot: Rat brain membrane lysate stained with ARG22233 anti-TRPC7 antibody [S64A-36] at 1:1000 dilution.
