ARG22233

anti-TRPC7 antibody [S64A-36]

anti-TRPC7 antibody [S64A-36] for Western blot,Immunohistochemistry,ICC/IF,Immunoprecipitation and Human,Mouse,Rat

Overview

Product Description Mouse Monoclonal antibody [S64A-36] recognizes TRPC7
Tested Reactivity Hu, Ms, Rat
Tested Application ICC/IF, IHC, IP, WB
Specificity Detects ~100kDa.
Host Mouse
Clonality Monoclonal
Clone S64A-36
Isotype IgG1
Target Name TRPC7
Antigen Species Human
Immunogen Synthetic peptide around aa. 845-862 of Human TrpC7
Conjugation Un-conjugated
Alternate Names hTRP7; Transient receptor protein 7; TrpC7; Short transient receptor potential channel 7; TRP-7; TRP7

Application Instructions

Application Suggestion
Tested Application Dilution
ICC/IF1:100
IHC1:1000
IPAssay-dependent
WB1:1000
Application Note * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

Properties

Form Liquid
Purification Purification with Protein G.
Buffer PBS (pH 7.4), 0.09% Sodium azide and 50% Glycerol
Preservative 0.09% Sodium azide
Stabilizer 50% Glycerol
Concentration 1 mg/ml
Storage Instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links

GeneID: 26946 Mouse TRPC7

GeneID: 57113 Human TRPC7

Swiss-port # Q9HCX4 Human Short transient receptor potential channel 7

Swiss-port # Q9WVC5 Mouse Short transient receptor potential channel 7

Gene Symbol TRPC7
Gene Full Name transient receptor potential cation channel, subfamily C, member 7
Function Thought to form a receptor-activated non-selective calcium permeant cation channel. Probably is operated by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases or G-protein coupled receptors. Activated by diacylglycerol (DAG) (By similarity). May also be activated by intracellular calcium store depletion. [UniProt]
Cellular Localization Membrane
Calculated MW 100 kDa
PTM Phosphorylation by PRKG1 at Thr-15 negatively regulates TRPC7 activity.

Images (1) Click the Picture to Zoom In

  • ARG22233 anti-TRPC7 antibody [S64A-36] WB image

    Western blot: Rat brain membrane lysate stained with ARG22233 anti-TRPC7 antibody [S64A-36] at 1:1000 dilution.