anti-TRPS1 antibody [SQab30333]

anti-TRPS1 antibody [SQab30333] for IHC-Formalin-fixed paraffin-embedded sections and Human


Product Description Recombinant rabbit Monoclonal antibody [SQab30333] recognizes TRPS1
Tested Reactivity Hu
Tested Application IHC-P
Host Rabbit
Clonality Monoclonal
Clone SQab30333
Isotype IgG
Target Name TRPS1
Antigen Species Human
Immunogen Synthetic peptide of Human TRPS1
Conjugation Un-conjugated
Protein Full Name Zinc finger transcription factor Trps1
Alternate Names TRPS1, Transcriptional Repressor GATA Binding 1, LGCR, GC79, Tricho-Rhino-Phalangeal Syndrome Type I Protein, Zinc Finger Transcription Factor Trps1, Trichorhinophalangeal Syndrome I, Zinc Finger Protein GC79

Application Instructions

Application Suggestion
Tested Application Dilution
IHC-P1:50 - 1:100
Application Note IHC-P: Antigen Retrieval: Heat mediated was performed using Tris/EDTA buffer (pH 9.0). Incubate the samples at RT (18-25°C) for 44 min.
* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
Positive Control Beast cancer


Form Liquid
Purification Purification with Protein A.
Buffer PBS, 0.01% Sodium azide, 40% Glycerol and 0.05%BSA.
Preservative 0.01% Sodium azide
Stabilizer 40% Glycerol and 0.05%BSA
Storage Instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.


Gene Symbol TRPS1
Gene Full Name Transcriptional Repressor GATA Binding 1
Background This gene encodes a transcription factor that represses GATA-regulated genes and binds to a dynein light chain protein. Binding of the encoded protein to the dynein light chain protein affects binding to GATA consensus sequences and suppresses its transcriptional activity. Defects in this gene are a cause of tricho-rhino-phalangeal syndrome (TRPS) types I-III. [provided by RefSeq, Jul 2008]
Function Transcriptional repressor. Binds specifically to GATA sequences and represses expression of GATA-regulated genes at selected sites and stages in vertebrate development. Regulates chondrocyte proliferation and differentiation. Executes multiple functions in proliferating chondrocytes, expanding the region of distal chondrocytes, activating proliferation in columnar cells and supporting the differentiation of columnar into hypertrophic chondrocytes. [UniProt]
Cellular Localization Nucleus
Calculated MW 141 kDa
PTM Sumoylated. Sumoylation in the repressor domain inhibits the transcription repression activity. Sumoylation on Lys-1201 is the major site. Appears to be sumoylated on multiple sites. [UniProt]

Images (1) Click the Picture to Zoom In

  • ARG67048 anti-TRPS1 antibody [SQab30333] IHC-P image

    Immunohistochemistry: Formalin-fixed and paraffin-embedded breast cancer stained with ARG67048 anti-TRPS1 antibody [SQab30333].