anti-TRPV3 antibody [S15-4]

anti-TRPV3 antibody [S15-4] for Western blot,Immunohistochemistry,ICC/IF,Immunoprecipitation and Human,Mouse,Rat


Product Description Mouse Monoclonal antibody [S15-4] recognizes TRPV3
Tested Reactivity Hu, Ms, Rat
Tested Application ICC/IF, IHC, IP, WB
Specificity Detects ~70kDa.
Host Mouse
Clonality Monoclonal
Clone S15-4
Isotype IgG2a
Target Name TRPV3
Antigen Species Rat
Immunogen Synthetic peptide around aa. 774-791 (C-terminus) of Rat TrpV3
Conjugation Un-conjugated
Alternate Names VRL3; VRL-3; TrpV3; Transient receptor potential cation channel subfamily V member 3; OLMS; Vanilloid receptor-like 3; FNEPPK2

Application Instructions

Application Suggestion
Tested Application Dilution
Application Note * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.


Form Liquid
Purification Purification with Protein G.
Buffer PBS (pH 7.4), 0.09% Sodium azide and 50% Glycerol
Preservative 0.09% Sodium azide
Stabilizer 50% Glycerol
Concentration 1 mg/ml
Storage Instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.


Database Links

GeneID: 162514 Human TRPV3

GeneID: 246788 Mouse TRPV3

Swiss-port # Q8K424 Mouse Transient receptor potential cation channel subfamily V member 3

Swiss-port # Q8NET8 Human Transient receptor potential cation channel subfamily V member 3

Gene Symbol Trpv3
Gene Full Name ransient receptor potential cation channel, subfamily V, member 3
Background This gene product belongs to a family of nonselective cation channels that function in a variety of processes, including temperature sensation and vasoregulation. The thermosensitive members of this family are expressed in subsets of sensory neurons that terminate in the skin, and are activated at distinct physiological temperatures. This channel is activated at temperatures between 22 and 40 degrees C. This gene lies in close proximity to another family member gene on chromosome 17, and the two encoded proteins are thought to associate with each other to form heteromeric channels. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2012]
Function Putative receptor-activated non-selective calcium permeant cation channel. It is activated by innocuous (warm) temperatures and shows an increased response at noxious temperatures greater than 39 degrees Celsius. Activation exhibits an outward rectification. May associate with TRPV1 and may modulate its activity. Is a negative regulator of hair growth and cycling: TRPV3-coupled signaling suppresses keratinocyte proliferation in hair follicles and induces apoptosis and premature hair follicle regression (catagen). [UniProt]
Cellular Localization Membrane
Calculated MW 91 kDa

Images (1) Click the Picture to Zoom In

  • ARG22283 anti-TRPV3 antibody [S15-4] WB image

    Western blot: Human cell lysates stained with ARG22283 anti-TRPV3 antibody [S15-4] at 1:1000 dilution.