ARG46620
anti-TYW1 antibody
anti-TYW1 antibody for Western blot,IHC-Formalin-fixed paraffin-embedded sections and Human,Rat
Overview
| Product Description | Rabbit Polyclonal antibody recognizes TYW1 |
|---|---|
| Tested Reactivity | Hu, Rat |
| Tested Application | IHC-P, WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | TYW1 |
| Antigen Species | Human |
| Immunogen | A 19 amino acid synthetic peptide within the last 50 amino acids of human TYW1. |
| Conjugation | Un-conjugated |
| Alternate Names | tRNA-yW synthesizing protein 1 homolog (S. cerevisiae); TYW1; TYW1A; RSAFD1; YPL207W; S-adenosyl-L-methionine-dependent tRNA 4-demethylwyosine synthase; Radical S-adenosyl methionine and flavodoxin domain-containing protein 1 |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity chromatography purified |
| Buffer | PBS and 0.02% Sodium azide. |
| Preservative | 0.02% Sodium azide |
| Concentration | 1 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -670°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links |
Swiss-port # Q9NV66 Human S-adenosyl-L-methionine-dependent tRNA 4-demethylwyosine synthase |
|---|---|
| Gene Symbol | TYW1 |
| Gene Full Name | tRNA-yW synthesizing protein 1 homolog (S. cerevisiae) |
| Background | Wybutosine (yW) is a hypermodified guanosine found in phenylalanine tRNA adjacent to the anticodon that stabilizes codon-anticodon interactions in the ribosome. In yeast, the homolog of this gene is essential for the synthesis of wybutosine. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2015] |
| Function | Probable component of the wybutosine biosynthesis pathway. Wybutosine is a hyper modified guanosine with a tricyclic base found at the 3'-position adjacent to the anticodon of eukaryotic phenylalanine tRNA. Catalyzes the condensation of N-methylguanine with 2 carbon atoms from pyruvate to form the tricyclic 4-demethylwyosine, an intermediate in wybutosine biosynthesis (By similarity). [UniProt] |
| Calculated MW | 84 kDa |
