anti-Thyroid Hormone Receptor beta antibody [2386]

anti-Thyroid Hormone Receptor beta antibody [2386] for Western blot and Human

Gene Regulation antibody; Neuroscience antibody; Signaling Transduction antibody


Product Description Mouse Monoclonal antibody [2386] recognizes Thyroid Hormone Receptor beta
Tested Reactivity Hu
Tested Application WB
Host Mouse
Clonality Monoclonal
Clone 2386
Isotype IgG1
Target Name Thyroid Hormone Receptor beta
Antigen Species Human
Immunogen Synthetic peptide corresponding to amino acid residues from the N-terminal region conjugated to KLH
Conjugation Un-conjugated
Alternate Names C-ERBA-2; NR1A2; THRB1; ERBA2; Nuclear receptor subfamily 1 group A member 2; GRTH; C-ERBA-BETA; c-erbA-2; Thyroid hormone receptor beta; PRTH; THRB2; c-erbA-beta; THR1

Application Instructions

Application Suggestion
Tested Application Dilution
Application Note Specific for the ~55k TR-β protein.
* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.


Form Liquid
Purification Protein G purified
Buffer 10 mM HEPES (pH 7.5), 150 mM NaCl, 0.1 mg/ml BSA and 50% Glycerol
Stabilizer 0.1 mg/ml BSA, 50% Glycerol
Storage Instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.


Database Links

GeneID: 7068 Human THRB

Swiss-port # P10828 Human Thyroid hormone receptor beta

Gene Symbol THRB
Gene Full Name thyroid hormone receptor, beta
Background Thyroid hormones are essential for development of the central nervous system and deficits in these hormones during development affects such cognitive functions as learning and memory (Ambrogini et al., 2005; Chan and Kilby, 2000). Thyroid hormones exert their physiological role mainly through binding to specific nuclear receptors including the predominant isoforms of thyroid hormone receptors TRα1, TRα2, TRβ1 and TRβ2. TRα1, TRβ1 and TRβ2 bind T3 with high affinity and also bind to thyroid hormone response elements (TREs) on chromatin to regulate the transcriptional processes in several target tissues, including adult rat brain (Constantinou et al., 2005).
Research Area Gene Regulation antibody; Neuroscience antibody; Signaling Transduction antibody
Calculated MW 53 kDa

Images (1) Click the Picture to Zoom In

  • ARG52448 anti-Thyroid Hormone Receptor beta antibody [2386] WB image

    Western blot: Hippocampal lysate showing specific immunolabeling of the ~58 kDa TR-β protein stained with ARG52448 anti-Thyroid Hormone Receptor beta antibody [2386].

Clone References

CXCR4 regulates interneuron migration in the developing neocortex.

IHC / Mouse

Stumm RK et al.
J Neurosci.,  (2003)