ARG10607

anti-Tissue Factor antibody

anti-Tissue Factor antibody for Western blot and Human

Overview

Product Description Rabbit Polyclonal antibody recognizes Tissue Factor
Tested Reactivity Hu
Tested Application WB
Host Rabbit
Clonality Polyclonal
Isotype IgG
Target Name Tissue Factor
Antigen Species Human
Immunogen Synthetic peptide around aa. 33-295 of Human Tissue Factor.
Conjugation Un-conjugated
Full Name coagulation factor III (thromboplastin, tissue factor)
Alternate Names Thromboplastin; Tissue factor; TFA; CD142; TF; Coagulation factor III; CD antigen CD142

Application Instructions

Application Suggestion
Tested Application Dilution
WB0.1 - 0.5 µg/ml
Application Note * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
Calculated MW 33 kDa (unmodified); 45-50 kDa (glycosylated)

Properties

Form Liquid
Purification Affinity purification with immunogen.
Buffer PBS, 0.025% Sodium azide and 2.5% BSA.
Preservative 0.025% Sodium azide
Stabilizer 2.5% BSA
Concentration 0.5 mg/ml
Storage instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database links

GeneID: 2152 Human F3

Swiss-port # P13726 Human Tissue factor

Gene Symbol F3
Gene Full Name coagulation factor III (thromboplastin, tissue factor)
Background This gene encodes coagulation factor III which is a cell surface glycoprotein. This factor enables cells to initiate the blood coagulation cascades, and it functions as the high-affinity receptor for the coagulation factor VII. The resulting complex provides a catalytic event that is responsible for initiation of the coagulation protease cascades by specific limited proteolysis. Unlike the other cofactors of these protease cascades, which circulate as nonfunctional precursors, this factor is a potent initiator that is fully functional when expressed on cell surfaces. There are 3 distinct domains of this factor: extracellular, transmembrane, and cytoplasmic. This protein is the only one in the coagulation pathway for which a congenital deficiency has not been described. Alternate splicing results in multiple transcript variants.[provided by RefSeq, May 2010]
Function Initiates blood coagulation by forming a complex with circulating factor VII or VIIa. The [TF:VIIa] complex activates factors IX or X by specific limited protolysis. TF plays a role in normal hemostasis by initiating the cell-surface assembly and propagation of the coagulation protease cascade. [UniProt]

Images (1) Click the Picture to Zoom In

  • ARG10607 anti-Tissue Factor antibody WB image

    Western blot: 1) Human placenta, 2) HeLa, and 3) HepG2 lysates stained with ARG10607 anti-Tissue Factor antibody.