ARG10448

anti-Transferrin antibody [2A2]

anti-Transferrin antibody [2A2] for ELISA and Human

Cell Biology and Cellular Response antibody; Controls and Markers antibody; Signaling Transduction antibody

Overview

Product Description Mouse Monoclonal antibody [2A2] recognizes Transferrin
Tested Reactivity Hu
Tested Application ELISA
Specificity MAb 2A2 reacts with N-terminal domain of human transferrin with Kd=2.85 x 10⎺11 M. MAbs 2A2 do not cross-react with mouse, rabbit, bovine transferrin and with human lactoferrin.
Host Mouse
Clonality Monoclonal
Clone 2A2
Isotype IgG1
Target Name Transferrin
Antigen Species Human
Immunogen purified transferrin from pooled human plasma
Conjugation Un-conjugated
Full Name transferrin
Alternate Names Beta-1 metal-binding globulin; Siderophilin; Transferrin; PRO1557; TFQTL1; Serotransferrin; PRO2086

Application Instructions

Application Note * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

Properties

Form Liquid
Purification Protein G affinity purified.
Buffer PBS (pH 7.4) and 0.1% Sodium azide
Preservative 0.1% Sodium azide
Concentration 1.0-2.0 mg/ml
Storage instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database links

GeneID: 7018 Human TF

Swiss-port # P02787 Human Serotransferrin

Gene Symbol TF
Gene Full Name transferrin
Background This gene encodes a glycoprotein with an approximate molecular weight of 76.5 kDa. It is thought to have been created as a result of an ancient gene duplication event that led to generation of homologous C and N-terminal domains each of which binds one ion of ferric iron. The function of this protein is to transport iron from the intestine, reticuloendothelial system, and liver parenchymal cells to all proliferating cells in the body. This protein may also have a physiologic role as granulocyte/pollen-binding protein (GPBP) involved in the removal of certain organic matter and allergens from serum. [provided by RefSeq, Sep 2009]
Function Transferrins are iron binding transport proteins which can bind two Fe(3+) ions in association with the binding of an anion, usually bicarbonate. It is responsible for the transport of iron from sites of absorption and heme degradation to those of storage and utilization. Serum transferrin may also have a further role in stimulating cell proliferation. [UniProt]
Research Area Cell Biology and Cellular Response antibody; Controls and Markers antibody; Signaling Transduction antibody