anti-Tyrosine Hydroxylase antibody
anti-Tyrosine Hydroxylase antibody for ICC/IF,Immunohistochemistry,Western blot and Human,Mammal,Mouse,Rat
Cancer antibody; Metabolism antibody; Neuroscience antibody
Sheep Polyclonal antibody recognizes Tyrosine Hydroxylase
|Tested Reactivity||Hu, Ms, Rat, Mamm|
|Tested Application||ICC/IF, IHC, WB|
|Target Name||Tyrosine Hydroxylase|
|Immunogen||Native rat tyrosine hydroxylase, purified from pheochromocytoma.|
|Alternate Names||DYT14; TYH; Tyrosine 3-monooxygenase; Tyrosine 3-hydroxylase; TH; DYT5b; EC 126.96.36.199|
|Application Note||Specific for the ~60k tyrosine hydroxylase protein.
Predict reacting to most mammals and some invertebrates.
* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
|Buffer||10 mM HEPES (pH 7.5), 150 mM NaCl, 0.1 mg/ml BSA and 50% Glycerol|
|Stabilizer||0.1 mg/ml BSA, 50% Glycerol|
|Storage Instruction||For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.|
|Note||For laboratory research only, not for drug, diagnostic or other use.|
|Gene Full Name||tyrosine hydroxylase|
|Background||Tyrosine hydroxylase (TH) is the rate-limiting enzyme in the synthesis of the catecholamines dopamine and norepinephrine. TH antibodies can therefore be used as markers for dopaminergic and noradrenergic neurons in a variety of applications including depression, schizophrenia, Parkinson’s disease and drug abuse (Kish et al., 2001; Zhu et al., 2000; Zhu et al., 1999). TH antibodies can also be used to explore basic mechanisms of dopamine and norepinephrine signaling (Witkovsky et al., 2000; Salvatore et al., 2001).|
Tyrosine Hydroxylase antibodies; Tyrosine Hydroxylase Duos / Panels; Anti-Sheep IgG secondary antibodies;
Astrocyte-to-neuron conversion for Parkinson's disease treatment
|Research Area||Cancer antibody; Metabolism antibody; Neuroscience antibody|
|Calculated MW||59 kDa|
Images (2) Click the Picture to Zoom In
ARG52462 anti-TH antibody WB image
Western Blot: 10 μg of rat caudate lysate showing specific immunolabeling of the ~ 60 k tyrosine hydroxylase proteins stained with TH antibody (ARG52462).
ARG52462 anti-TH antibody IHC image
Immunohistochemistry: rabbit retina stained with ARG52462 anti-TH antibody showing specific labeling of tyrosine hydroxylase in green.