ARG46631
anti-UROP11 antibody
anti-UROP11 antibody for Western blot and Human,Mouse,Rat
Overview
| Product Description | Rabbit Polyclonal antibody recognizes UROP11 |
|---|---|
| Tested Reactivity | Hu, Ms, Rat |
| Tested Application | WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | UROP11 |
| Antigen Species | Mouse |
| Immunogen | A 12 amino acid synthetic peptide within the last 50 amino acids of mouse UROP11. |
| Conjugation | Un-conjugated |
| Alternate Names | Apba1; amyloid beta (A4) precursor protein binding, family A, member 1; UROP11; X11; Mint; Mint1; Lin-10; Urop11; X11alpha; 6430513E09Rik; X11; Amyloid beta A4 precursor protein-binding family A member 1; Adapter protein X11alpha; Mint-1 |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity chromatography purified |
| Buffer | PBS and 0.02% Sodium azide. |
| Preservative | 0.02% Sodium azide |
| Concentration | 1 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -681°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Gene Symbol | Apba1 |
|---|---|
| Gene Full Name | amyloid beta (A4) precursor protein binding, family A, member 1 |
| Background | Predicted to enable several functions, including PDZ domain binding activity; amyloid-beta binding activity; and phosphatidylinositol-4,5-bisphosphate binding activity. Involved in presynaptic modulation of chemical synaptic transmission. Acts upstream of or within several processes, including carboxylic acid transport; in utero embryonic development; and locomotory behavior. Located in membrane. Is active in Schaffer collateral - CA1 synapse; glutamatergic synapse; and presynaptic active zone membrane. Is expressed in central nervous system and dorsal root ganglion. Orthologous to human APBA1 (amyloid beta precursor protein binding family A member 1). [provided by Alliance of Genome Resources, Jul 2025] |
| Function | Putative function in synaptic vesicle exocytosis by binding to Munc18-1, an essential component of the synaptic vesicle exocytotic machinery. May modulate processing of the amyloid-beta precursor protein (APP) and hence formation of AAP-beta (By similarity). Component of the LIN-10-LIN-2-LIN-7 complex, which associates with the motor protein KIF17 to transport vesicles containing N-methyl-D-aspartate (NMDA) receptor subunit NR2B along microtubules (PubMed:10846156). [UniProt] |
| Cellular Localization | Cytoplasm; Nucleus; Golgi apparatus. [UniProt] |
| Calculated MW | 93 kDa |
| PTM | Phosphoprotein. [UniProt] |
