ARG46719

anti-VIP antibody

anti-VIP antibody for IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Mouse,Rat

Overview

Product Description Rabbit Polyclonal antibody recognizes VIP
Tested Reactivity Hu, Ms, Rat
Tested Application IHC-P, WB
Host Rabbit
Clonality Polyclonal
Isotype IgG
Target Name VIP
Conjugation Un-conjugated
Alternate Names Vasoactive intestinal polypeptide; PHM27; VIP peptides; Peptide histidine valine 42; VIP; Peptide histidine methioninamide 27

Application Instructions

Application Suggestion
Tested Application Dilution
IHC-P1:50 - 1:200
WB1:500 - 1:2000
Application Note * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

Properties

Form Liquid
Purification Affinity chromatography purified
Buffer PBS, Sodium azide and 50% Glycerol
Preservative Sodium azide
Stabilizer 50% Glycerol
Storage Instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links

GeneID: 117064 Rat VIP

GeneID: 22353 Mouse VIP

GeneID: 7432 Human VIP

Gene Symbol VIP
Gene Full Name vasoactive intestinal peptide
Background The protein encoded by this gene belongs to the glucagon family. It stimulates myocardial contractility, causes vasodilation, increases glycogenolysis, lowers arterial blood pressure and relaxes the smooth muscle of trachea, stomach and gall bladder. The protein also acts as an antimicrobial peptide with antibacterial and antifungal activity. Alternative splicing occurs at this locus and two transcript variants encoding distinct isoforms have been identified. [provided by RefSeq, Nov 2014]
Function VIP causes vasodilation, lowers arterial blood pressure, stimulates myocardial contractility, increases glycogenolysis and relaxes the smooth muscle of trachea, stomach and gall bladder.

PHM and PHV also cause vasodilation. PHM-27 is a potent agonist of the calcitonin receptor CALCR, with similar efficacy as calcitonin. [UniProt]
Cellular Localization Secreted. [UniProt]
Calculated MW 19 kDa

Images (2) Click the Picture to Zoom In

  • ARG46719 anti-VIP antibody IHC-P image

    Immunohistochemistry: Human Esophagus stained with ARG46719 anti-VIP antibody.

  • ARG46719 anti-VIP antibody WB image

    Western blot: Rat spinal cord stained with ARG46719 anti-VIP antibody.