anti-VPAC2 antibody [SP235]

anti-VPAC2 antibody [SP235] for Flow cytometry,IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Mouse,Rat

Cancer antibody; Cell Biology and Cellular Response antibody; Controls and Markers antibody; Neuroscience antibody; Signaling Transduction antibody
publication_link Publication2


Product Description

Rabbit Monoclonal antibody [SP235] recognizes VPAC2

Tested Reactivity Hu, Ms, Rat
Tested Application FACS, IHC-P, WB
Host Rabbit
Clonality Monoclonal
Clone SP235
Isotype IgG
Target Name VPAC2
Antigen Species Human
Immunogen Synthetic peptide LQFHRGSRAQSFLQTETSVI corresponds to amino acids 419–428 of the human VPAC2.
Conjugation Un-conjugated
Alternate Names PACAP-R3; VPAC2; Vasoactive intestinal polypeptide receptor 2; DUP7q36.3; Pituitary adenylate cyclase-activating polypeptide type III receptor; VIP-R-2; C16DUPq36.3; PACAP type III receptor; VPCAP2R; VPAC2R; Helodermin-preferring VIP receptor; PACAP-R-3

Application Instructions

Application Suggestion
Tested Application Dilution
Application Note * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
Positive Control Tonsil


Form Liquid
Purification Purified by protein A/G
Buffer PBS (pH 7.6), 1% BSA and < 0.1% Sodium azide
Preservative < 0.1% Sodium azide
Stabilizer 1% BSA
Storage Instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.


Database Links

GeneID: 22355 Mouse VIPR2

GeneID: 29555 Rat VIPR2

GeneID: 7434 Human VIPR2

Gene Symbol VIPR2
Gene Full Name vasoactive intestinal peptide receptor 2
Background This gene encodes a receptor for vasoactive intestinal peptide, a small neuropeptide. Vasoactive intestinal peptide is involved in smooth muscle relaxation, exocrine and endocrine secretion, and water and ion flux in lung and intestinal epithelia. Its actions are effected through integral membrane receptors associated with a guanine nucleotide binding protein which activates adenylate cyclase. [provided by RefSeq, Aug 2011]
Function This is a receptor for VIP as well as PACAP-38 and -27, the activity of this receptor is mediated by G proteins which activate adenylyl cyclase. Can be coupled to phospholipase C. [UniProt]
Cellular Localization Cytoplasm, Membrane
Research Area Cancer antibody; Cell Biology and Cellular Response antibody; Controls and Markers antibody; Neuroscience antibody; Signaling Transduction antibody
Calculated MW 49 kDa

Images (1) Click the Picture to Zoom In

  • ARG53727 anti-VPAC2 antibody [SP235] IHC-P image

    Immunohistochemistry: Human Tonsil stained with VPAC2 antibody [SP235] (ARG53727)

Specific References

Postmenopausal osteoporosis is associated with the regulation of SP, CGRP, VIP, and NPY.

WB / Rat

Liu Xiaoguang et al.
Biomed Pharmacother.,  (2018)




Effects of water extract from epimedium on neuropeptide signaling in an ovariectomized osteoporosis rat model.

WB / Rat

Liu Hengrui et al.
J Ethnopharmacol.,  (2018)