ARG46095
anti-VPS13B antibody
anti-VPS13B antibody for Western blot and Human,Mouse,Rat
Overview
| Product Description | Rabbit Polyclonal antibody recognizes VPS13B |
|---|---|
| Tested Reactivity | Hu, Ms, Rat |
| Tested Application | WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | VPS13B |
| Antigen Species | Human |
| Immunogen | A 17 amino acid synthetic peptide within aa. 90 - 140 of human VPS13B. |
| Conjugation | Un-conjugated |
| Alternate Names | VPS13B; vacuolar protein sorting 13 homolog B (yeast); COH1; CHS1; COH1; CHS1; KIAA0532; Vacuolar protein sorting-associated protein 13B; Cohen syndrome protein 1 |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity chromatography purified |
| Buffer | PBS and 0.02% Sodium azide. |
| Preservative | 0.02% Sodium azide |
| Concentration | 1 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -145°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links |
Swiss-port # Q7Z7G8 Human Vacuolar protein sorting-associated protein 13B Swiss-port # Q80TY5 Mouse Vacuolar protein sorting-associated protein 13B |
|---|---|
| Gene Symbol | VPS13B |
| Gene Full Name | vacuolar protein sorting 13 homolog B (yeast) |
| Background | This gene encodes a potential transmembrane protein that may function in vesicle-mediated transport and sorting of proteins within the cell. This protein may play a role in the development and the function of the eye, hematological system, and central nervous system. Mutations in this gene have been associated with Cohen syndrome. Multiple splice variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jul 2008] |
| Function | Mediates the transfer of lipids between membranes at organelle contact sites (By similarity). Binds phosphatidylinositol 3-phosphate (By similarity). Functions as a tethering factor in the slow endocytic recycling pathway, to assist traffic between early and recycling endosomes. [UniProt] |
| Cellular Localization | Cytoplasm; Endosome; Lysosome membrane; Cytoplasmic vesicle; Recycling endosome membrane; Golgi apparatus. [UniProt] |
| Calculated MW | 449 kDa |
| PTM | Phosphoprotein. [UniProt] |
