ARG24191
anti-Versican antibody [N351/23]
anti-Versican antibody [N351/23] for ICC/IF,Western blot and Human,Mouse,Rat
Overview
| Product Description | Mous Monoclonal antibody [N351/23] recognizes Versican |
|---|---|
| Tested Reactivity | Hu, Ms, Rat |
| Tested Application | ICC/IF, WB |
| Host | Mouse |
| Clonality | Monoclonal |
| Clone | N351/23 |
| Isotype | IgG1 |
| Target Name | Versican |
| Antigen Species | Mouse |
| Immunogen | Fusion protein amino acids 362-585 (glycosaminoglycan alpha domain) of mouse Versican core protein |
| Conjugation | Un-conjugated |
| Alternate Names | CSPG2; Glial hyaluronate-binding protein; Chondroitin sulfate proteoglycan 2; WGN; WGN1; Versican core protein; PG-M; Large fibroblast proteoglycan; ERVR; GHAP; Chondroitin sulfate proteoglycan core protein 2 |
Application Instructions
| Application Suggestion |
|
||||||
|---|---|---|---|---|---|---|---|
| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||
| Observed Size | 350 kDa |
Properties
| Form | Liquid |
|---|---|
| Purification | Purification with Protein G |
| Buffer | PBS, 0.1% Sodium azide and 50% Glycerol. |
| Preservative | 0.1% Sodium azide |
| Stabilizer | 50% Glycerol |
| Concentration | 1 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | VCAN |
| Gene Full Name | versican |
| Background | This gene is a member of the aggrecan/versican proteoglycan family. The protein encoded is a large chondroitin sulfate proteoglycan and is a major component of the extracellular matrix. This protein is involved in cell adhesion, proliferation, proliferation, migration and angiogenesis and plays a central role in tissue morphogenesis and maintenance. Mutations in this gene are the cause of Wagner syndrome type 1. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2009] |
| Function | May play a role in intercellular signaling and in connecting cells with the extracellular matrix. May take part in the regulation of cell motility, growth and differentiation. Binds hyaluronic acid. [UniProt] |
| Cellular Localization | Secreted, extracellular space, extracellular matrix. [UniProt] |
| Calculated MW | 373 kDa |
| PTM | Phosphorylated by FAM20C in the extracellular medium. [UniProt] |
Images (3) Click the Picture to Zoom In
-
ARG24191 anti-Versican antibody [N351/23] ICC/IF image
Immunofluorescence: SK-N-BE stained with ARG24191 anti-Versican antibody [N351/23] at 1:100 dilution.
-
ARG24191 anti-Versican antibody [N351/23] ICC/IF image
Immunofluorescence: SH-SY5Y stained with ARG24191 anti-Versican antibody [N351/23] at 1:200 dilution.
-
ARG24191 anti-Versican antibody [N351/23] WB image
Western blot: Rat Brain stained with ARG24191 anti-Versican antibody [N351/23] at 1:200 dilution.
