ARG67252
anti-n Myc antibody [SQab30370]
anti-n Myc antibody [SQab30370] for IHC-Formalin-fixed paraffin-embedded sections and Human
. [Uniprot]
Overview
| Product Description | Rabbit Monoclonal antibody [SQab30370] recognizes n Myc. |
|---|---|
| Tested Reactivity | Hu |
| Tested Application | IHC-P |
| Host | Rabbit |
| Clonality | Monoclonal |
| Clone | SQab30370 |
| Isotype | IgG |
| Target Name | n Myc |
| Antigen Species | Human |
| Immunogen | Synthetic peptide corresponding to Human n Myc. |
| Conjugation | Un-conjugated |
| Alternate Names | MYCN; MYCN Proto-Oncogene, BHLH Transcription Factor; BHLHe37; N-Myc; NMYC; V-Myc Avian Myelocytomatosis Viral Oncogene Neuroblastoma Derived Homolog; Class E Basic Helix-Loop-Helix Protein 37; N-Myc Proto-Oncogene Protein; MYCNOT; Neuroblastoma-Derived V-Myc Avian Myelocytomatosis Viral Related Oncogene; Neuroblastoma MYC Oncogene; Oncogene NMYC; MYCNsORF; MYCNsPEP; BHLHE37; FGLDS1; MODED; MPAPA; ODED |
Application Instructions
| Application Suggestion |
|
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|---|---|---|---|---|---|
| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Purification with Protein A. |
| Buffer | PBS, 0.01% Sodium azide, 40% Glycerol and 0.05% BSA. |
| Preservative | 0.01% Sodium azide |
| Stabilizer | 40% Glycerol and 0.05% BSA |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | MYCN |
| Gene Full Name | MYCN Proto-Oncogene, BHLH Transcription Factor |
| Background | This gene is a member of the MYC family and encodes a protein with a basic helix-loop-helix (bHLH) domain. This protein is located in the nucleus and must dimerize with another bHLH protein in order to bind DNA. Amplification of this gene is associated with a variety of tumors, most notably neuroblastomas. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2014] |
| Function | Positively regulates the transcription of MYCNOS in neuroblastoma cells. [Uniprot] |
| Cellular Localization | Nucleus. [Uniprot] |
| Highlight | . [Uniprot] |
| Research Area | . [Uniprot] |
| Calculated MW | 50 kDa |
| PTM | Phosphoprotein. [Uniprot] |
Images (1) Click the Picture to Zoom In
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ARG67252 anti-n Myc antibody [SQab30370] IHC-P image
Immunohistochemistry: Human Neuroblastoma stained with ARG67252 anti-n Myc antibody [SQab30370] at 1:100 dilution.
