ARG10205

anti-serum Amyloid A antibody [607] (HRP)

anti-serum Amyloid A antibody [607] (HRP) for ELISA and Human

Cell Biology and Cellular Response antibody; Metabolism antibody

Overview

Product Description

HRP-conjugated Mouse Monoclonal antibody [607] recognizes Human serum Amyloid A

Tested Reactivity Hu
Tested Application ELISA
Specificity Does not show any cross-reaction with other human cytokines or growth factors tested such as IL-1β, IL-8, MCAF, TGF-β and EGF.
Host Mouse
Clonality Monoclonal
Clone 607
Isotype IgG2a,k
Target Name serum Amyloid A
Antigen Species Human
Immunogen Highly purified recombinant human serum Amyloid A (MW: 12 kDa)
Conjugation HRP
Alternate Names 2-104; 2-103; 2-102; Serum amyloid A-1 protein; TP53I4; SAA; Amyloid fibril protein AA; SAA2; PIG4; 4-101; 3-104

Application Instructions

Application Note ELISA: This HRP conjugated antibody can be used as a detection antibody in sandwich ELISA applications for human SAA detection.

* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

Properties

Form Liquid
Purification Protein G affinity purified
Buffer 0.01M PBS (pH 7.2) and 50% Glycerol
Stabilizer 50% Glycerol
Storage instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Keep the antibody in the dark and keep protected from prolonged exposure to light. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database links

GeneID: 6288 Human SAA1

Swiss-port # P0DJI8 Human Serum amyloid A-1 protein

Gene Symbol SAA1
Gene Full Name serum amyloid A1
Background SAA is an acute phase protein and a sensitive inflammatory marker. Cytokines such as IL-1, IL-6 and TNF-alpha stimulates hepatocytes to produce and release SAA. In acute phase, SAA in blood can increase to more than 1,000 folds of normal level. Prolonged and repeated elevation of SAA results in abnormal deposition of amyloid proteins in organ or tissue in insoluble beta pleated form. Determination of SAA levels is important for assessment of renal allograft rejection, estimation of tissue damage caused by myocardial infarction and severe angina, and diagnosis of inflammation in cystic fibrosis patients and in patients infected with virus.
Function Major acute phase protein. [UniProt]
Resrarch Area Cell Biology and Cellular Response antibody; Metabolism antibody
PTM This protein is the precursor of amyloid protein A, which is formed by the removal of approximately 24 residues from the C-terminal end.