ARG83719
arigoQIK® Human CD120a / TNFR1 ELISA Development Kit
arigoQIK® Human CD120a / TNFR1 ELISA Development Kit for ELISA and Human
Overview
| Product Description | ARG83719 arigoQIK® Human CD120a / TNFR1 ELISA Development Kit, includes Capture antibody, Detection antibody, Standard, and HRP-Streptavidin Solution. This ELISA Development Kit is designed for the development of sandwich ELISA to measure Human CD120a / TNFR1 in Serum, plasma and cell culture supernatants. For other reagents required for arigoQIK® ELISA Development Kit, please refer ARG83524 Integral Reagent Kit (ELISA Development Kit) More aboutarigoQIK® : ● Optimized capture and detection antibody pairs ● Reduced incubation time and wash cycles ● 2-hour quicker than conventional ELISA process ● 5- and 15-plate packages available |
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| Tested Reactivity | Hu |
| Tested Application | ELISA |
| Target Name | CD120a / TNFR1 |
| Conjugation | HRP |
| Conjugation Note | Substrate: TMB and read at 450 nm. |
| Sensitivity | 0.05 pg/mL |
| Sample Type | Serum, plasma and cell culture supernatants. |
| Standard Range | 0.08-5 pg/mL |
| Sample Volume | 50 μL |
| Precision | Intra-Assay CV: < 10% Inter-Assay CV: < 10% |
| Alternate Names | TNFRSF1A; TNF Receptor Superfamily Member 1A; TNFAR; TNF-R-I; TNF-R55; TNFR60; CD120a; TNF-R; TNFR1; Tumor Necrosis Factor Receptor Superfamily Member 1A; TNF-R1; TNF-RI; TNFR-I; P55; P60; Tumor Necrosis Factor Receptor Superfamily, Member 1A; Tumor Necrosis Factor Binding Protein 1; Tumor Necrosis Factor Receptor Type 1; Tumor Necrosis Factor Receptor Type I; Tumor Necrosis Factor-Alpha Receptor; Tumor Necrosis Factor Receptor 1; CD120a Antigen; TNFR55; P55-R; TBP1; FPF |
Properties
| Storage Instruction | Store components at 4°C or -20°C. Do not expose test reagents to heat, sun or strong light during storage and usage. Please refer to the product user manual for detail temperatures of the components. |
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| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links |
Swiss-port # P19438 Human Tumor necrosis factor receptor superfamily member 1A |
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| Gene Symbol | TNFRSF1A |
| Gene Full Name | TNF Receptor Superfamily Member 1A |
| Background | This gene encodes a member of the TNF receptor superfamily of proteins. The encoded receptor is found in membrane-bound and soluble forms that interact with membrane-bound and soluble forms, respectively, of its ligand, tumor necrosis factor alpha. Binding of membrane-bound tumor necrosis factor alpha to the membrane-bound receptor induces receptor trimerization and activation, which plays a role in cell survival, apoptosis, and inflammation. Proteolytic processing of the encoded receptor results in release of the soluble form of the receptor, which can interact with free tumor necrosis factor alpha to inhibit inflammation. Mutations in this gene underlie tumor necrosis factor receptor-associated periodic syndrome (TRAPS), characterized by fever, abdominal pain and other features. Mutations in this gene may also be associated with multiple sclerosis in human patients. [provided by RefSeq, Sep 2016] |
| Function | Receptor for TNFSF2/TNF-alpha and homotrimeric TNFSF1/lymphotoxin-alpha. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. Contributes to the induction of non-cytocidal TNF effects including anti-viral state and activation of the acid sphingomyelinase. [Uniprot] |
| Title | Download Link |
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| ARG83719 arigoQIK® Human CD120a / TNFR1 ELISA Development Kit User manual |
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