ARG83679
arigoQIK® Human CD123 / IL3RA ELISA Development Kit
arigoQIK® Human CD123 / IL3RA ELISA Development Kit for ELISA and Human
Overview
| Product Description | ARG83679 arigoQIK® Human CD123 / IL3RA ELISA Development Kit, includes Capture antibody, Detection antibody, Standard, and HRP-Streptavidin Solution. This ELISA Development Kit is designed for the development of sandwich ELISA to measure Human CD123 / IL3RA in Serum, plasma and cell culture supernatants. For other reagents required for arigoQIK® ELISA Development Kit, please refer ARG83524 Integral Reagent Kit (ELISA Development Kit) More aboutarigoQIK® : ● Optimized capture and detection antibody pairs ● Reduced incubation time and wash cycles ● 2-hour quicker than conventional ELISA process ● 5- and 15-plate packages available |
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| Tested Reactivity | Hu |
| Tested Application | ELISA |
| Target Name | CD123 / IL3RA |
| Conjugation | HRP |
| Conjugation Note | Substrate: TMB and read at 450 nm. |
| Sensitivity | 0.4 ng/mL |
| Sample Type | Serum, plasma and cell culture supernatants. |
| Standard Range | 0.78-50 ng/mL |
| Sample Volume | 50 μL |
| Precision | Intra-Assay CV: < 10% Inter-Assay CV: < 10% |
| Alternate Names | IL3RA; Interleukin 3 Receptor Subunit Alpha; CD123; Interleukin 3 Receptor, Alpha (Low Affinity); Interleukin-3 Receptor Subunit Alpha; IL-3 Receptor Subunit Alpha; IL-3R Subunit Alpha; CD123 Antigen; IL-3R-Alpha; IL3R; HIL-3Ra; IL3RAY; IL-3RA; IL3RX; IL3RY |
Properties
| Storage Instruction | Store components at 4°C or -20°C. Do not expose test reagents to heat, sun or strong light during storage and usage. Please refer to the product user manual for detail temperatures of the components. |
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| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links |
Swiss-port # P26951 Human Interleukin-3 receptor subunit alpha |
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| Gene Symbol | IL3RA |
| Gene Full Name | Interleukin 3 Receptor Subunit Alpha |
| Background | The protein encoded by this gene is an interleukin 3 specific subunit of a heterodimeric cytokine receptor. The receptor is comprised of a ligand specific alpha subunit and a signal transducing beta subunit shared by the receptors for interleukin 3 (IL3), colony stimulating factor 2 (CSF2/GM-CSF), and interleukin 5 (IL5). The binding of this protein to IL3 depends on the beta subunit. The beta subunit is activated by the ligand binding, and is required for the biological activities of IL3. This gene and the gene encoding the colony stimulating factor 2 receptor alpha chain (CSF2RA) form a cytokine receptor gene cluster in a X-Y pseudoautosomal region on chromosomes X or Y. Alternatively spliced transcript variants encoding distinct isoforms have been found. [provided by RefSeq, Jun 2012] |
| Function | Ligand stimulation rapidly induces hetrodimerization with IL3RB, phosphorylation and enzyme activity of effector proteins such as JAK2 and PI3K that play a role in signaling cell proliferation and differentiation. Activation of JAK2 leads to STAT5-mediated transcriptional program. [Uniprot] |
| Title | Download Link |
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| ARG83679 arigoQIK® Human CD123 IL3RA ELISA Development Kit User manual |
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