ARG83708

arigoQIK® Human FOLR1 ELISA Development Kit

arigoQIK® Human FOLR1 ELISA Development Kit for ELISA and Human

Overview

Product Description ARG83708 arigoQIK® Human FOLR1 ELISA Development Kit, includes Capture antibody, Detection antibody, Standard, and HRP-Streptavidin Solution.
This ELISA Development Kit is designed for the development of sandwich ELISA to measure Human FOLR1 in Serum, plasma and cell culture supernatants.

For other reagents required for arigoQIK® ELISA Development Kit, please refer ARG83524 Integral Reagent Kit (ELISA Development Kit)

More aboutarigoQIK® :
● Optimized capture and detection antibody pairs
● Reduced incubation time and wash cycles
● 2-hour quicker than conventional ELISA process
● 5- and 15-plate packages available
Tested Reactivity Hu
Tested Application ELISA
Target Name FOLR1
Conjugation HRP
Conjugation Note Substrate: TMB and read at 450 nm.
Sensitivity 0.15 pg/mL
Sample Type Serum, plasma and cell culture supernatants.
Standard Range 0.23-15 pg/mL
Sample Volume 50 μL
Precision Intra-Assay CV: < 10%
Inter-Assay CV: < 10%
Alternate Names FOLR1; Folate Receptor Alpha; FOLR; Ovarian Tumor-Associated Antigen MOv18; Adult Folate-Binding Protein; Folate Receptor 1 (Adult); Folate Receptor, Adult; Folate Receptor 1; KB Cells FBP; FR-Alpha; FBP; Folate Binding Protein; FRalpha; NCFTD; FRα; FRA

Properties

Storage Instruction Store components at 4°C or -20°C. Do not expose test reagents to heat, sun or strong light during storage and usage. Please refer to the product user manual for detail temperatures of the components.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links

GeneID: 2348 Human FOLR1

Swiss-port # P15328 Human Folate receptor alpha

Gene Symbol FOLR1
Gene Full Name Folate Receptor Alpha
Background The protein encoded by this gene is a member of the folate receptor family. Members of this gene family bind folic acid and its reduced derivatives, and transport 5-methyltetrahydrofolate into cells. This gene product is a secreted protein that either anchors to membranes via a glycosyl-phosphatidylinositol linkage or exists in a soluble form. Mutations in this gene have been associated with neurodegeneration due to cerebral folate transport deficiency. Due to the presence of two promoters, multiple transcription start sites, and alternative splicing, multiple transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Oct 2009]
Function Exposure to slightly acidic pH after receptor endocytosis triggers a conformation change that strongly reduces its affinity for folates and mediates their release.
Required for normal embryonic development and normal cell proliferation. [Uniprot]
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