ARG83708
arigoQIK® Human FOLR1 ELISA Development Kit
arigoQIK® Human FOLR1 ELISA Development Kit for ELISA and Human
Overview
Product Description | ARG83708 arigoQIK® Human FOLR1 ELISA Development Kit, includes Capture antibody, Detection antibody, Standard, and HRP-Streptavidin Solution. This ELISA Development Kit is designed for the development of sandwich ELISA to measure Human FOLR1 in Serum, plasma and cell culture supernatants. For other reagents required for arigoQIK® ELISA Development Kit, please refer ARG83524 Integral Reagent Kit (ELISA Development Kit) More aboutarigoQIK® : ● Optimized capture and detection antibody pairs ● Reduced incubation time and wash cycles ● 2-hour quicker than conventional ELISA process ● 5- and 15-plate packages available |
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Tested Reactivity | Hu |
Tested Application | ELISA |
Target Name | FOLR1 |
Conjugation | HRP |
Conjugation Note | Substrate: TMB and read at 450 nm. |
Sensitivity | 0.15 pg/mL |
Sample Type | Serum, plasma and cell culture supernatants. |
Standard Range | 0.23-15 pg/mL |
Sample Volume | 50 μL |
Precision | Intra-Assay CV: < 10% Inter-Assay CV: < 10% |
Alternate Names | FOLR1; Folate Receptor Alpha; FOLR; Ovarian Tumor-Associated Antigen MOv18; Adult Folate-Binding Protein; Folate Receptor 1 (Adult); Folate Receptor, Adult; Folate Receptor 1; KB Cells FBP; FR-Alpha; FBP; Folate Binding Protein; FRalpha; NCFTD; FRα; FRA |
Properties
Storage Instruction | Store components at 4°C or -20°C. Do not expose test reagents to heat, sun or strong light during storage and usage. Please refer to the product user manual for detail temperatures of the components. |
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Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
Database Links | |
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Gene Symbol | FOLR1 |
Gene Full Name | Folate Receptor Alpha |
Background | The protein encoded by this gene is a member of the folate receptor family. Members of this gene family bind folic acid and its reduced derivatives, and transport 5-methyltetrahydrofolate into cells. This gene product is a secreted protein that either anchors to membranes via a glycosyl-phosphatidylinositol linkage or exists in a soluble form. Mutations in this gene have been associated with neurodegeneration due to cerebral folate transport deficiency. Due to the presence of two promoters, multiple transcription start sites, and alternative splicing, multiple transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Oct 2009] |
Function | Exposure to slightly acidic pH after receptor endocytosis triggers a conformation change that strongly reduces its affinity for folates and mediates their release. Required for normal embryonic development and normal cell proliferation. [Uniprot] |
Title | Download Link |
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ARG83708 arigoQIK® Human FOLR1 ELISA Development Kit |
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