ARG83709
arigoQIK® Human Granzyme A ELISA Development Kit
arigoQIK® Human Granzyme A ELISA Development Kit for ELISA and Human
Overview
| Product Description | ARG83709 arigoQIK® Human Granzyme A ELISA Development Kit, includes Capture antibody, Detection antibody, Standard, and HRP-Streptavidin Solution. This ELISA Development Kit is designed for the development of sandwich ELISA to measure Human Granzyme A in Serum, plasma and cell culture supernatants. For other reagents required for arigoQIK® ELISA Development Kit, please refer ARG83524 Integral Reagent Kit (ELISA Development Kit) More aboutarigoQIK® : ● Optimized capture and detection antibody pairs ● Reduced incubation time and wash cycles ● 2-hour quicker than conventional ELISA process ● 5- and 15-plate packages available |
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| Tested Reactivity | Hu |
| Tested Application | ELISA |
| Target Name | Granzyme A |
| Conjugation | HRP |
| Conjugation Note | Substrate: TMB and read at 450 nm. |
| Sensitivity | 0.1 pg/mL |
| Sample Type | Serum, plasma and cell culture supernatants. |
| Standard Range | 0.156-10 pg/mL |
| Sample Volume | 50 μL |
| Precision | Intra-Assay CV: < 10% Inter-Assay CV: < 10% |
| Alternate Names | GZMA; Granzyme A; CTL Tryptase; CTLA3; HFSP; Granzyme A (Granzyme 1, Cytotoxic T-Lymphocyte-Associated Serine Esterase 3); Cytotoxic T-Lymphocyte-Associated Serine Esterase-3; Cytotoxic T-Lymphocyte Proteinase 1; Hanukah Factor Serine Protease); Fragmentin-1; Granzyme 1; H Factor; HF; Granzyme A (Cytotoxic T-Lymphocyte-Associated Serine Esterase-3; Hanukah Factor Serine Protease); Hanukkah Factor; EC 3.4.21.78; Granzyme-1; EC 3.4.21 |
Properties
| Storage Instruction | Store components at 4°C or -20°C. Do not expose test reagents to heat, sun or strong light during storage and usage. Please refer to the product user manual for detail temperatures of the components. |
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| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
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| Gene Symbol | GZMA |
| Gene Full Name | Granzyme A |
| Background | Cytolytic T lymphocytes (CTL) and natural killer (NK) cells share the remarkable ability to recognize, bind, and lyse specific target cells. They are thought to protect their host by lysing cells bearing on their surface 'nonself' antigens, usually peptides or proteins resulting from infection by intracellular pathogens. The protein described here is a T cell- and natural killer cell-specific serine protease that may function as a common component necessary for lysis of target cells by cytotoxic T lymphocytes and natural killer cells. [provided by RefSeq, Jul 2008] |
| Function | Cleaves the nucleosome assembly protein SET after 'Lys-189', which disrupts its nucleosome assembly activity and allows the SET complex to translocate into the nucleus to nick and degrade the DNA. [Uniprot] |
| Title | Download Link |
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| ARG83709 arigoQIK® Human Granzyme A ELISA Development Kit User manual |
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