ARG83683

arigoQIK® Human IL18 binding protein ELISA Development Kit

arigoQIK® Human IL18 binding protein ELISA Development Kit for ELISA and Human

Overview

Product Description ARG83683 arigoQIK® Human IL18 binding protein ELISA Development Kit, includes Capture antibody, Detection antibody, Standard, and HRP-Streptavidin Solution.
This ELISA Development Kit is designed for the development of sandwich ELISA to measure Human IL18 binding protein in Serum, plasma and cell culture supernatants.

For other reagents required for arigoQIK® ELISA Development Kit, please refer ARG83524 Integral Reagent Kit (ELISA Development Kit)

More aboutarigoQIK® :
● Optimized capture and detection antibody pairs
● Reduced incubation time and wash cycles
● 2-hour quicker than conventional ELISA process
● 5- and 15-plate packages available
Tested Reactivity Hu
Tested Application ELISA
Target Name IL18 binding protein
Conjugation HRP
Conjugation Note Substrate: TMB and read at 450 nm.
Sensitivity 0.25 ng/mL
Sample Type Serum, plasma and cell culture supernatants.
Standard Range 0.47-30 ng/mL
Sample Volume 50 μL
Precision Intra-Assay CV: < 10%
Inter-Assay CV: < 10%
Alternate Names IL18BP; Interleukin 18 Binding Protein; IL18BPa; MC51L-53L-54L Homolog Gene Product; Interleukin-18-Binding Protein; Tadekinig-Alfa; IL-18BP; FVH

Properties

Storage Instruction Store components at 4°C or -20°C. Do not expose test reagents to heat, sun or strong light during storage and usage. Please refer to the product user manual for detail temperatures of the components.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links

GeneID: 10068 Human IL18BP

Swiss-port # O95998 Human Interleukin-18-binding protein

Gene Symbol IL18BP
Gene Full Name Interleukin 18 Binding Protein
Background The protein encoded by this gene functions as an inhibitor of the proinflammatory cytokine, IL18. It binds IL18, prevents the binding of IL18 to its receptor, and thus inhibits IL18-induced IFN-gamma production, resulting in reduced T-helper type 1 immune responses. This protein is constitutively expressed and secreted in mononuclear cells. Elevated level of this protein is detected in the intestinal tissues of patients with Crohn's disease. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Feb 2011]
Function Isoform A binds to IL-18 and inhibits its activity. Functions as an inhibitor of the early TH1 cytokine response. [Uniprot]
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