ARG83713
arigoQIK® Human MICB ELISA Development Kit
arigoQIK® Human MICB ELISA Development Kit for ELISA and Human
Overview
| Product Description | ARG83713 arigoQIK® Human MICB ELISA Development Kit, includes Capture antibody, Detection antibody, Standard, and HRP-Streptavidin Solution. This ELISA Development Kit is designed for the development of sandwich ELISA to measure Human MICB in Serum, plasma and cell culture supernatants. For other reagents required for arigoQIK® ELISA Development Kit, please refer ARG83524 Integral Reagent Kit (ELISA Development Kit) More aboutarigoQIK® : ● Optimized capture and detection antibody pairs ● Reduced incubation time and wash cycles ● 2-hour quicker than conventional ELISA process ● 5- and 15-plate packages available |
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| Tested Reactivity | Hu |
| Tested Application | ELISA |
| Target Name | MICB |
| Conjugation | HRP |
| Conjugation Note | Substrate: TMB and read at 450 nm. |
| Sensitivity | 0.2 pg/mL |
| Sample Type | Serum, plasma and cell culture supernatants. |
| Standard Range | 0.39-25 pg/mL |
| Sample Volume | 50 μL |
| Precision | Intra-Assay CV: < 10% Inter-Assay CV: < 10% |
| Alternate Names | MICB; MHC Class I Polypeptide-Related Sequence B; PERB11.2; MHC Class I-Like Molecule PERB11.2-IMX; MHC Class I Antigen-Related Protein B; MHC Class I Chain-Related Protein B; Stress Inducible Class I Homolog; MHC Class I Mic-B Antigen; MIC-B |
Properties
| Storage Instruction | Store components at 4°C or -20°C. Do not expose test reagents to heat, sun or strong light during storage and usage. Please refer to the product user manual for detail temperatures of the components. |
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| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links |
Swiss-port # Q29980 Human MHC class I polypeptide-related sequence B |
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| Gene Symbol | MICB |
| Gene Full Name | MHC Class I Polypeptide-Related Sequence B |
| Background | This gene encodes a heavily glycosylated protein which is a ligand for the NKG2D type II receptor. Binding of the ligand activates the cytolytic response of natural killer (NK) cells, CD8 alphabeta T cells, and gammadelta T cells which express the receptor. This protein is stress-induced and is similar to MHC class I molecules; however, it does not associate with beta-2-microglobulin or bind peptides. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014] |
| Function | Up-regulated in stressed conditions, such as viral and bacterial infections or DNA damage response, serves as signal of cellular stress, and engagement of KLRK1/NKG2D by MICA triggers NK-cells resulting in a range of immune effector functions, such as cytotoxicity and cytokine production. [Uniprot] |
| Title | Download Link |
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| ARG83713 arigoQIK® Human MICB ELISA Development Kit User manual |
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