ARG30007

Astrocyte Marker Antibody Duo (Host: Goat, Rabbit)

Controls and Markers antibody; Developmental Biology antibody; Neuroscience antibody; Signaling Transduction antibody
publication_link Publication1

Component

Cat No Component Name Host clonality Reactivity Application Package
ARG52312 anti-GFAP antibody Rabbit pAb Cat, Dog, Hu, Ms, Rat ICC/IF, IHC-P, IHC-Fr, IHC-FoFr , WB 50 μl
ARG64066 anti-GFAP antibody Goat pAb Hu, Ms, Rat IHC-P, IHC-Fr, WB 50 μg

Overview

Product Description Glial fibrillary acidic protein (GFAP) is the major intermediate filament protein in mature astrocytes, a main type of glial cells in the central nervous system (CNS). GFAP is used as a marker to distinguish astrocytes from other glial cells during development.

If the CNS is injured through acute CNS trauma, ischemia or neurodegenerative diseases, astrocytes react by rapidly producing more GFAP. Upregulation of GFAP expression has become a pathological hallmark of CNS lesions.

arigo's ARG30007 Astrocyte Marker Antibody Duo (Host: Goat, Rabbit) comprises both rabbit and goat anti-GFAP antibodies that are excellent solution for co-staining with other neural lineage marker or brain injury marker.

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Target Name Astrocyte Marker
Alternate Names Astrocyte Marker antibody; GFAP antibody

Properties

Storage Instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Gene Full Name Antibody Duo for Astrocyte Marker
Research Area Controls and Markers antibody; Developmental Biology antibody; Neuroscience antibody; Signaling Transduction antibody

Images (7) Click the Picture to Zoom In

  • ARG64066 anti-GFAP antibody WB image

    Western blot: 20 µg of Mouse brain and Rat brain lysates stained with ARG64066 anti-GFAP antibody at 1:5000 dilution.

  • ARG52312 anti-GFAP antibody IHC-Fr image

    Immunohistochemistry: Frozen section of Mouse C57BL/6Jnarl brain tissue. The tissue section was fixed by 4% formalin and blocked with BSA with 3% Goat serum, at RT for 1 hour. Tissue section was then stained with ARG52312 anti-GFAP antibody at 1:500 dilution, in PBS with 1% Goat serum, overnight at 4°C.

    Blue: DAPI
    Yellow: Venus reporter gene
    Red: GFAP

  • ARG52312 anti-GFAP antibody ICC/IF image

    Immunofluorescence: Cultured neurons and glia stained with ARG52312 anti-GFAP antibody (red) and ARG52468 anti-Vimentin antibody (green) showing specific labeling of GFAP (red) and vimentin (green). Cells containing GFAP and vimentin appear yellow

  • ARG64066 anti-GFAP antibody IHC-Fr image

    Immunohistochemistry: PFA-perfused cryosection of Human hypothalamus tissue stained with ARG64066 anti-GFAP antibody at 0.01 µg/ml dilution.

  • ARG64066 anti-GFAP antibody IHC-P image

    Immunohistochemistry: Paraffin-embedded Human cortex tissue. Antigen Retrieval: Steam tissue section in Citrate buffer (pH 6.0). The tissue section was stained with ARG64066 anti-GFAP antibody at 5 µg/ml dilution followed by AP-staining.

  • ARG64066 anti-GFAP antibody IHC-P image

    Immunohistochemistry: Paraffin-embedded Human cerebellum tissue. Antigen Retrieval: Steam tissue section in Citrate buffer (pH 6.0). The tissue section was stained with ARG64066 anti-GFAP antibody at 2 µg/ml dilution, followed by HRP-staining.

  • ARG52312 anti-GFAP antibody WB image

    Western blot: Rat cortex lysate showing specific immunolabeling of the ~50 kDa GFAP protein stained with ARG52312 anti-GFAP antibody.

Specific References

Toll-Like Receptor 4 Mediates Methamphetamine-Induced Neuroinflammation through Caspase-11 Signaling Pathway in Astrocytes.

ARG52312: IHC-P, IHC-Fr / Mouse

Du Si-Hao et al.
Front. Mol. Neurosci.,  (2017)

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