ARG30336

Human MDSC Marker Antibody Duo

Myeloid-derived suppressor cells marker; MDSCs marker; Tumor immune microenvironment; tumor-associated myeloid cells

Component

Cat No Component Name Host clonality Reactivity Application Package
ARG22000 anti-CD11b antibody [M1/70] Rat mAb Bb, Hu, Ms, R. Mk BL, FACS, ICC/IF, IHC-Fr, IP 50 μg
ARG65560 anti-CD33 antibody [WM53] Mouse mAb Hu, NHuPrm CyTOF®-candidate, FACS, FuncSt, ICC/IF, IHC-Fr, IP, WB 50 μg

Overview

Product Description

Human MDSC Marker Antibody Duo includes antibodies to MDSC marker, CD11b and CD33, for Myeloid-derived suppressor cells (MDSCs) study.

Myeloid-derived suppressor cells (MDSCs) are a heterogeneous population of immune cells from the myeloid lineage. MDSCs are well-known key negative regulators of the immune response in tumor microenvironment. Accumulated evidences show that MDSCs may serve as a therapeutic target for preventing tumor progression.

In humam, MDSCs are defined as cells expressing CD33 and CD11b. arigo’s Human MDSC Marker Antibody Duo comprises CD33 and CD11b antibodies. It is the best solution to identify the MDSCs in human tumor tissues.

Target Name Human MDSC marker
Full Name Human Myeloid-derived suppressor cell (MDSC) marker Antibody Duo
Alternate Names Human MDSC Marker antibody; Myeloid-derived suppressor cells marker antibody; MDSCs marker antibody; CD11b antibody; CD33 antibody

Properties

Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Gene Full Name Human Myeloid-derived suppressor cell (MDSC) marker Antibody Duo
Highlight Related products:
MDSC Duos / Panels;
Related news:
New antibody panels and duos for Tumor immune microenvironment
Research Area Myeloid-derived suppressor cells marker; MDSCs marker; Tumor immune microenvironment; tumor-associated myeloid cells

Images (4) Click the Picture to Zoom In

  • ARG65560 anti-CD33 antibody [WM53] IHC-Fr image

    Immunohistochemistry: Frozen section of Human colon tissue stained with ARG65560 anti-CD33 antibody [WM53].

  • ARG22000 anti-CD11b antibody [M1/70] IHC-Fr image

    Immunohistochemistry: Cryosection of Mouse lymph node stained with ARG22000 anti-CD11b antibody [M1/70] (green, A) and anti-Mouse CD8 antibody (red, B). Merged image in C.

  • ARG65560 anti-CD33 antibody [WM53] FACS image

    Flow Cytometry: Separation of Human CD33 positive Monocytes (red) from Human CD33 negative Lymphocytes (black-dashed). Human peripheral blood stained with ARG65560 anti-CD33 antibody [WM53], followed by incubation with APC labelled Goat anti-Mouse secondary antibody.

  • ARG65560 anti-CD33 antibody [WM53] FACS image

    Flow Cytometry: PBMC stained with ARG65560 anti-CD33 antibody [WM53] at 0.5 µg/10^6 cells (right histogram) or isotype control (left histogram), followed by incubation with PE labelled secondary antibody.