ARG30344

Necrosome Antibody Panel

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Component

Cat No Component Name Host clonality Reactivity Application Package
ARG55746 anti-RIPK1 / RIP1 antibody Rabbit pAb Hu, Ms, Rat ICC/IF, WB 20 μg
ARG54926 anti-RIPK3 / RIP3 antibody Rabbit pAb Hu, Ms, Rat ELISA, ICC/IF, IHC-P, IHC-Fr, IP, WB 20 μg
ARG41397 anti-MLKL antibody Rabbit pAb Hu, Ms WB, IHC-P 20 μl

Overview

Product Description Related news:
RIP1 activation and pathogenesis of NASH

Properties

Storage Instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Images (9) Click the Picture to Zoom In

  • ARG54926 anti-RIPK3 / RIP3 antibody ICC/IF image

    Immunofluorescence: Rat kidney cells stained with ARG54926 anti-RIPK3 / RIP3 antibody at 20 µg/ml dilution.

  • ARG55746 anti-RIPK1 / RIP1 antibody ICC/IF image

    Immunofluorescence: Mouse Kidney cells stained with ARG55746 anti-RIPK1 / RIP1 antibody at 20 µg/ml dilution.

  • ARG54926 anti-RIPK3 / RIP3 antibody IHC-P image

    Immunohistochemistry: Paraffin-embedded Mouse kidney tissue. Tissue was fixed with formaldehyde and blocked with 10% serum for 1 hour at RT. Antigen Retrieval: Heat mediation was performed in Citrate buffer (pH 6.0). The tissue section was stained with ARG54926 anti-RIPK3 / RIP3 antibody at 2.5 µg/ml dilution, overnight at 4°C. Counter stained with Hematoxylin.

  • ARG41397 anti-MLKL antibody IHC-P image

    Immunohistochemistry: Paraffin-embedded Human colon tissue stained with ARG41397 anti-MLKL antibody.

  • ARG54926 anti-RIPK3 / RIP3 antibody WB image

    Western blot: 15 µg of A431 cell lysate stained with ARG54926 anti-RIPK3 / RIP3 antibody at 0.5 µg/ml dilution and incubated at RT for 1 hour.

  • ARG55746 anti-RIPK1 / RIP1 antibody WB image

    Western blot: Rat kidney tissue lysate stained with ARG55746 anti-RIPK1 / RIP1 antibody at 1 µg/ml dilution.

  • ARG41397 anti-MLKL antibody WB image

    Western blot: SW480 cell lysate stained with ARG41397 anti-MLKL antibody at 1:1000 dilution.

  • ARG54926 anti-RIPK3 / RIP3 antibody IHC-P image

    Immunohistochemistry: Paraffin-embedded Rat kidney tissue. Tissue was fixed with formaldehyde and blocked with 10% serum for 1 hour at RT. Antigen Retrieval: Heat mediation was performed in Citrate buffer (pH 6.0). The tissue section was stained with ARG54926 anti-RIPK3 / RIP3 antibody at 5 µg/ml dilution, overnight at 4°C. Counter stained with Hematoxylin.

  • ARG54926 anti-RIPK3 / RIP3 antibody WB image

    Western blot: 15 µg of C2C12 cell lysate stained with ARG54926 anti-RIPK3 / RIP3 antibody at 0.5 µg/ml dilution and incubated at RT for 1 hour.

Specific References

RIP3/MLKL pathway-regulated necroptosis: A new mechanism of paclitaxel-induced peripheral neuropathy

ARG54926: WB / Rat

Dongyang Ma et al.
J Biochem Mol Toxicol.,  (2021)

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