ARG20920

anti-CD38 antibody [NIMR-5] (PE)

anti-CD38 antibody [NIMR-5] (PE) for Blocking,Cellular activation ,Flow cytometry,IHC-Frozen sections and Mouse

Cancer antibody; Developmental Biology antibody; Immune System antibody; Metabolism antibody; Pro-B Cell Marker antibody; Pre-B Cell Marker antibody

Overview

Product Description PE-conjugated Rat Monoclonal antibody [NIMR-5] recognizes CD38
Tested Reactivity Ms
Tested Application BL, Cell-Act , FACS, IHC-Fr
Specificity Mouse CD38.
Host Rat
Clonality Monoclonal
Clone NIMR-5
Isotype IgG2a, kappa
Target Name CD38
Antigen Species Mouse
Immunogen BCL1 plasma membrane glycoproteins
Conjugation PE
Full Name CD38 antigen
Alternate Names cADPr hydrolase 1; ADPRC 1; EC 3.2.2.6; 2'-phospho-ADP-ribosyl cyclase/2'-phospho-cyclic-ADP-ribose transferase; Cyclic ADP-ribose hydrolase 1; ADPRC1; EC 2.4.99.20; ADP-ribosyl cyclase 1; 2'-phospho-cyclic-ADP-ribose transferase; CD antigen CD38; T10; 2'-phospho-ADP-ribosyl cyclase; ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1

Application Instructions

Application Suggestion
Tested Application Dilution
BLAssay-dependent
Cell-Act Assay-dependent
FACS< 0.2 µg/10^6 cells
IHC-FrAssay-dependent
Application Note * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
Calculated MW 34 kDa

Properties

Form Liquid
Buffer PBS, Sodium azide and a stabilizing agent
Preservative Sodium azide
Concentration 0.1 mg/ml
Storage instruction Aliquot and store in the dark at 2-8°C. Keep protected from prolonged exposure to light. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database links

GeneID: 12494 Mouse CD38

Swiss-port # P56528 Mouse ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1

Gene Symbol CD38
Gene Full Name CD38 antigen
Background The protein encoded by this gene is a non-lineage-restricted, type II transmembrane glycoprotein that synthesizes and hydrolyzes cyclic adenosine 5'-diphosphate-ribose, an intracellular calcium ion mobilizing messenger. The release of soluble protein and the ability of membrane-bound protein to become internalized indicate both extracellular and intracellular functions for the protein. This protein has an N-terminal cytoplasmic tail, a single membrane-spanning domain, and a C-terminal extracellular region with four N-glycosylation sites. Crystal structure analysis demonstrates that the functional molecule is a dimer, with the central portion containing the catalytic site. It is used as a prognostic marker for patients with chronic lymphocytic leukemia. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2015]
Function Synthesizes the second messagers cyclic ADP-ribose and nicotinate-adenine dinucleotide phosphate, the former a second messenger for glucose-induced insulin secretion. Also has cADPr hydrolase activity. Also moonlights as a receptor in cells of the immune system. [UniProt]
Research Area Cancer antibody; Developmental Biology antibody; Immune System antibody; Metabolism antibody; Pro-B Cell Marker antibody; Pre-B Cell Marker antibody

Images (1) Click the Picture to Zoom In

  • ARG20920 anti-CD38 antibody [NIMR-5] (PE) FACS image

    Flow Cytometry: BALB/c Mouse splenocytes stained with ARG20920 anti-CD38 antibody [NIMR-5] (PE) and ARG65532 anti-CD45R / B220 antibody [RA3-6B2] (FITC).