anti-CD8b antibody [EP42] (PE)

anti-CD8b antibody [EP42] (PE) for Flow cytometry,IHC-Frozen sections and Chicken


Product Description

PE-conjugated Mouse Monoclonal antibody [EP42] recognizes CD8b

Tested Reactivity Chk
Tested Application FACS, IHC-Fr
Specificity Chicken CD8β. The clone EP42 recognizes the CD8β chain.
Host Mouse
Clonality Monoclonal
Clone EP42
Isotype IgG2a, kappa
Target Name CD8b
Antigen Species Chicken
Immunogen Chicken splenocytes
Conjugation PE
Alternate Names LY3; CD8B1; CD antigen CD8b; LEU2; T-cell surface glycoprotein CD8 beta chain; P37; LYT3

Application Instructions

Application Suggestion
Tested Application Dilution
FACS< 0.2 µg/10^6 cells
Application Note * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.


Form Liquid
Buffer PBS, 0.1% Sodium azide and Sucrose.
Preservative 0.1% Sodium azide
Stabilizer Sucrose
Concentration 0.1 mg/ml
Storage Instruction Aliquot and store in the dark at 2-8°C. Keep protected from prolonged exposure to light. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.


Gene Symbol CD8B
Gene Full Name CD8b molecule
Background The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. The CD8 antigen, acting as a coreceptor, and the T-cell receptor on the T lymphocyte recognize antigens displayed by an antigen presenting cell (APC) in the context of class I MHC molecules. The functional coreceptor is either a homodimer composed of two alpha chains, or a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains. This gene encodes the CD8 beta chain isoforms. Multiple alternatively spliced transcript variants encoding distinct membrane associated or secreted isoforms have been described. A pseudogene, also located on chromosome 2, has been identified. [provided by RefSeq, May 2010]
Function Identifies cytotoxic/suppressor T-cells that interact with MHC class I bearing targets. CD8 is thought to play a role in the process of T-cell mediated killing. [UniProt]
Highlight Related products:
CD8 antibodies; CD8 ELISA Kits; CD8 Duos / Panels; Anti-Mouse IgG secondary antibodies;
Related news:
New antibody panels and duos for Tumor immune microenvironment
Tumor-Infiltrating Lymphocytes (TILs)
Calculated MW 24 kDa
PTM Phosphorylated as a consequence of T-cell activation.

Images (2) Click the Picture to Zoom In

  • ARG21195 anti-CD8b antibody [EP42] (PE) FACS image

    Flow Cytometry: Chicken peripheral blood mononuclear cells stained with ARG21195 anti-CD8b antibody [EP42] (PE) and ARG21156 anti-CD4 antibody [CT-4] (FITC).

  • ARG21195 anti-CD8b antibody [EP42] (PE) FACS image

    Flow Cytometry: Chicken peripheral blood lymphocytes stained with ARG21195 anti-CD8b antibody [EP42] (PE) and ARG21156 anti-CD4 antibody [CT-4] (FITC).