ARG10565

anti-Cytokeratin 19 antibody [E16-L]

anti-Cytokeratin 19 antibody [E16-L] for IHC-Formalin-fixed paraffin-embedded sections and Human

Overview

Product Description Rabbit Monoclonal antibody [E16-L] recognizes Cytokeratin 19
Tested Reactivity Hu
Tested Application IHC-P
Host Rabbit
Clonality Monoclonal
Clone E16-L
Isotype IgG
Target Name Cytokeratin 19
Antigen Species Human
Immunogen Synthetic peptide around the C-terminus of Human cytokeratin 19
Conjugation Un-conjugated
Full Name keratin 19, type I
Alternate Names Cytokeratin-19; K19; CK-19; K1CS; Keratin-19; CK19; Keratin, type I cytoskeletal 19

Application Instructions

Application Suggestion
Tested Application Dilution
IHC-P1:100 - 1:200
Application Note * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

Properties

Form Liquid
Buffer 20 mM Tris-HCl (pH 8.0), 0.05% Sodium azide and 20 mg/ml BSA
Preservative 0.05% Sodium azide
Stabilizer 20 mg/ml BSA
Storage instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database links

GeneID: 3880 Human KRT19

Swiss-port # P08727 Human Keratin, type I cytoskeletal 19

Gene Symbol KRT19
Gene Full Name keratin 19, type I
Background The protein encoded by this gene is a member of the keratin family. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. The type I cytokeratins consist of acidic proteins which are arranged in pairs of heterotypic keratin chains. Unlike its related family members, this smallest known acidic cytokeratin is not paired with a basic cytokeratin in epithelial cells. It is specifically expressed in the periderm, the transiently superficial layer that envelopes the developing epidermis. The type I cytokeratins are clustered in a region of chromosome 17q12-q21. [provided by RefSeq, Jul 2008]
Function Involved in the organization of myofibers. Together with KRT8, helps to link the contractile apparatus to dystrophin at the costameres of striated muscle. [UniProt]

Images (2) Click the Picture to Zoom In

  • ARG10565 anti-Cytokeratin 19 antibody [E16-L] IHC-P image

    Immunohistochemistry: Formalin fixed, paraffin embedded Human epithelial thymoma tissue (4 µm section) stained with ARG10565 anti-Cytokeratin 19 antibody [E16-L].

  • ARG10565 anti-Cytokeratin 19 antibody [E16-L] IHC-P image

    Immunohistochemistry: Formalin fixed, paraffin embedded Human monophasic spindle cell synovial sarcoma tissue (4 µm section) stained with ARG10565 anti-Cytokeratin 19 antibody [E16-L].