ARG45197
anti-GCHFR antibody
anti-GCHFR antibody for Flow cytometry,ICC/IF,IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Mouse,Rat
Overview
| Product Description | Rabbit Polyclonal antibody recognizes GCHFR |
|---|---|
| Tested Reactivity | Hu, Ms, Rat |
| Tested Application | FACS, ICC/IF, IHC-P, WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | GCHFR |
| Antigen Species | Human |
| Immunogen | Recombinant protein containing to human GCHFR. |
| Conjugation | Un-conjugated |
| Alternate Names | GCHFR; GTP Cyclohydrolase I Feedback Regulator; GFRP; GTP Cyclohydrolase I Feedback Regulatory Protein; HsT16933; GTP Cyclohydrolase 1 Feedback Regulatory Protein; P35 |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||||||
| Observed Size | 12 kDa |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purification with immunogen. |
| Buffer | 0.9% NaCl, 0.2% Na2HPO4, 0.005% Sodium azide and 4% Trehalose. |
| Preservative | 0.005% Sodium azide |
| Stabilizer | 4% Trehalose |
| Concentration | 0.5 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | GCHFR |
| Gene Full Name | GTP Cyclohydrolase I Feedback Regulator |
| Background | GTP cyclohydrolase I feedback regulatory protein binds to and mediates tetrahydrobiopterin inhibition of GTP cyclohydrolase I. The regulatory protein, GCHFR, consists of a homodimer. It is postulated that GCHFR may play a role in regulating phenylalanine metabolism in the liver and in the production of biogenic amine neurotransmitters and nitric oxide. [provided by RefSeq, Jul 2008] |
| Function | Mediates tetrahydrobiopterin inhibition of GTP cyclohydrolase 1. This inhibition is reversed by L-phenylalanine.. [UniProt] |
| Cellular Localization | Cytoplasm; Membrane; Nucleus. [UniProt] |
| Calculated MW | 10 kDa |
Images (7) Click the Picture to Zoom In
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ARG45197 anti-GCHFR antibody IHC-P image
Immunohistochemistry: Human rectal cancer stained with ARG45197 anti-GCHFR antibody at 2 μg/ml dilution.
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ARG45197 anti-GCHFR antibody ICC/IF image
Immunofluorescence: CACO-2 stained with ARG45197 anti-GCHFR antibody at 5 ug/ml dilution.
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ARG45197 anti-GCHFR antibody WB image
Western blot: HEPG2, CACO-2, U937, and PC-3 stained with ARG45197 anti-GCHFR antibody at 0.5 μg/ml dilution.
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ARG45197 anti-GCHFR antibody FACS image
Flow Cytometry: HL-60 stained with ARG45197 anti-GCHFR antibody at 1 µg/10^6 cells dilution.
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ARG45197 anti-GCHFR antibody WB image
Western blot: Rat liver stained with ARG45197 anti-GCHFR antibody at 0.5 μg/ml dilution.
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ARG45197 anti-GCHFR antibody IHC-P image
Immunohistochemistry: Mouse liver stained with ARG45197 anti-GCHFR antibody at 2 μg/ml dilution.
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ARG45197 anti-GCHFR antibody WB image
Western blot: Mouse liver stained with ARG45197 anti-GCHFR antibody at 0.5 μg/ml dilution.
