ARG66497

anti-GLUT1 antibody

anti-GLUT1 antibody for IHC-Formalin-fixed paraffin-embedded sections and Human

Overview

Product Description Mouse Monoclonal antibody recognizes GLUT1
Tested Reactivity Hu
Tested Application IHC-P
Host Mouse
Clonality Monoclonal
Isotype IgG2a, kappa
Target Name GLUT1
Antigen Species Human
Immunogen Synthetic peptide derived from Human GLUT1.
Conjugation Un-conjugated
Alternate Names DYT17; HepG2 glucose transporter; CSE; GLUT-1; GLUT; GLUT1DS; DYT18; HTLVR; PED; Glucose transporter type 1, erythrocyte/brain; DYT9; EIG12; GLUT1; Solute carrier family 2, facilitated glucose transporter member 1

Application Instructions

Application Suggestion
Tested Application Dilution
IHC-P1:100 - 1:500
Application Note IHC-P: Antigen Retrieval: Tris/EDTA buffer (pH 8.0) was used.
* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

Properties

Form Liquid
Purification Affinity purification with immunogen.
Buffer PBS, 0.02% Sodium azide, 50% Glycerol and 0.5% BSA.
Preservative 0.02% Sodium azide
Stabilizer 50% Glycerol and 0.5% BSA
Concentration 1 mg/ml
Storage Instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links

GeneID: 6513 Human SLC2A1

Swiss-port # P11166 Human Solute carrier family 2, facilitated glucose transporter member 1

Gene Symbol SLC2A1
Gene Full Name solute carrier family 2 (facilitated glucose transporter), member 1
Background This gene encodes a major glucose transporter in the mammalian blood-brain barrier. The encoded protein is found primarily in the cell membrane and on the cell surface, where it can also function as a receptor for human T-cell leukemia virus (HTLV) I and II. Mutations in this gene have been found in a family with paroxysmal exertion-induced dyskinesia. [provided by RefSeq, Apr 2013]
Function Facilitative glucose transporter. This isoform may be responsible for constitutive or basal glucose uptake. Has a very broad substrate specificity; can transport a wide range of aldoses including both pentoses and hexoses. [UniProt]
Cellular Localization Cell membrane; Multi-pass membrane protein. Melanosome. Note=Localizes primarily at the cell surface. Identified by mass spectrometry in melanosome fractions from stage I to stage IV. [UniProt]
Calculated MW 54 kDa

Images (1) Click the Picture to Zoom In

  • ARG66497 anti-GLUT1 antibody IHC-P image

    Immunohistochemistry: Paraffin-embedded Human colon carcinoma stained with ARG66497 anti-GLUT1 antibody at 1:200 (4°C, overnight). Antigen Retrieval: Tris/EDTA buffer (pH 8.0) was used.