ARG45689

anti-MYH6 antibody

anti-MYH6 antibody for Flow cytometry,IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Mouse,Rat

Overview

Product Description Rabbit Polyclonal antibody recognizes MYH6
Tested Reactivity Hu, Ms, Rat
Tested Application FACS, IHC-P, WB
Host Rabbit
Clonality Polyclonal
Isotype IgG
Target Name MYH6
Antigen Species Human
Immunogen Synthetic peptide corresponding to middle region of human MYH6.
Conjugation Un-conjugated
Alternate Names MYH6; Myosin Heavy Chain 6; Myosin, Heavy Polypeptide 6, Cardiac Muscle, Alpha (Cardiomyopathy, Hypertrophic 1); MyHC-Alpha; Myosin-6; MYHCA; Myosin Heavy Chain, Cardiac Muscle Alpha Isoform; Cardiomyopathy, Hypertrophic 1; Alpha-MHC; CMD1EE; CMH14; ASD3; MYHC; SSS3

Application Instructions

Application Suggestion
Tested Application Dilution
FACS1 - 3 µg/10^6 cells
IHC-P2-5 μg/ml
WB0.25-0.5 μg/ml
Application Note * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

Properties

Form Liquid
Purification Affinity purified
Buffer 0.2% Na2HPO4, 0.9% NaCl and 4% Trehalose.
Stabilizer 4% Trehalose
Concentration 0.5 mg/ml
Storage Instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links

GeneID: 17888 Mouse MYH6

GeneID: 4624 Human MYH6

Swiss-port # P13533 Human Myosin-6

Swiss-port # Q02566 Mouse Myosin-6

Gene Symbol MYH6
Gene Full Name Myosin Heavy Chain 6
Background Cardiac muscle myosin is a hexamer consisting of two heavy chain subunits, two light chain subunits, and two regulatory subunits. This gene encodes the alpha heavy chain subunit of cardiac myosin. The gene is located approximately 4kb downstream of the gene encoding the beta heavy chain subunit of cardiac myosin. Mutations in this gene cause familial hypertrophic cardiomyopathy and atrial septal defect 3. [provided by RefSeq, Feb 2017]
Function Muscle contraction. [UniProt]
Cellular Localization Cytoplasm; Thick filament. [UniProt]
Calculated MW 224 kDa
PTM Methylation; Phosphoprotein. [UniProt]

Images (5) Click the Picture to Zoom In

  • ARG45689 anti-MYH6 antibody IHC-P image

    Immunohistochemistry: Human skeletal muscle stained with ARG45689 anti-MYH6 antibody at 2 μg/ml dilution.

  • ARG45689 anti-MYH6 antibody FACS image

    Flow Cytometry: U937 stained with ARG45689 anti-MYH6 antibody at 1 µg/10^6 cells dilution.

  • ARG45689 anti-MYH6 antibody IHC-P image

    Immunohistochemistry: Rat cardiac stained with ARG45689 anti-MYH6 antibody at 2 μg/ml dilution.

  • ARG45689 anti-MYH6 antibody IHC-P image

    Immunohistochemistry: Mouse cardiac stained with ARG45689 anti-MYH6 antibody at 2 μg/ml dilution.

  • ARG45689 anti-MYH6 antibody WB image

    Western blot: Mouse heart stained with ARG45689 anti-MYH6 antibody at 0.5 μg/ml dilution.