ARG10794

anti-PDE2A antibody

anti-PDE2A antibody for Confocal microscopy (Confocal),Dot blot,ELISA,Fluorescence Resonance Energy Transfer,ICC/IF,IHC-Formalin-fixed paraffin-embedded sections,IHC-Whole mount,Immunoprecipitation,Western blot and Bovine,Human,Mouse,Rat

publication_link Publication1

Overview

Product Description Rabbit Polyclonal antibody recognizes PDE2A
Tested Reactivity Hu, Ms, Rat, Bov
Tested Application Confocal, Dot, ELISA, FRET, ICC/IF, IHC-P, IHC-Wmt, IP, WB
Host Rabbit
Clonality Polyclonal
Isotype IgG
Target Name PDE2A
Species Human
Immunogen Synthetic peptide around the C-terminus of Human PDE2A.
Conjugation Un-conjugated
Full Name phosphodiesterase 2A, cGMP-stimulated
Alternate Names EC 3.1.4.17; CGS-PDE; PDE2A1; PED2A4; cGMP-dependent 3',5'-cyclic phosphodiesterase; Cyclic GMP-stimulated phosphodiesterase; cGSPDE

Application Instructions

Application Suggestion
Tested Application Dilution
Confocal1:250 - 1:1000
Dot1:10000
ELISA1:10000
FRETAssay-dependent
ICC/IF1:150 - 1:1000
IHC-P1:250 - 1:1000
IHC-WmtAssay-dependent
IP1:200
WB1:250 - 1:1000
Application Note * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
Calculated MW 106 kDa

Properties

Form Liquid
Purification Affinity purified.
Buffer Tris-Glycine Buffer (pH 7.4 - 7.8), Hepes, 0.02% Sodium azide, 30% Glycerol and 0.5% BSA.
Preservative 0.02% Sodium azide
Stabilizer 30% Glycerol and 0.5% BSA
Concentration 0.5 mg/ml
Storage instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database links

GeneID: 281971 Bovine PDE2A

GeneID: 5138 Human PDE2A

GeneID: 81743 Rat PDE2A

Gene Symbol PDE2A
Gene Full Name phosphodiesterase 2A, cGMP-stimulated
Function Cyclic nucleotide phosphodiesterase with a dual-specificity for the second messengers cAMP and cGMP, which are key regulators of many important physiological processes.

Isoform PDE2A2: Regulates Mitochondrial cAMP Levels and Respiration. [UniProt]

Images (5) Click the Picture to Zoom In

  • ARG10794 anti-PDE2A antibody IHC-Wmt image

    Immunohistochemistry: Whole-mount Mouse nose stained with ARG10794 anti-PDE2A antibody (red). Green: Grueneberg ganglion neurons. Blue: Nuclei.

  • ARG10794 anti-PDE2A antibody WB image

    Western blot: 10 ng of recombinant PDE2A stained with ARG10794 anti-PDE2A antibody at 1:500 dilution.

  • ARG10794 anti-PDE2A antibody IHC-Wmt image

    Immunohistochemistry: Whole-mount Mouse nose stained with ARG10794 anti-PDE2A antibody (red). Green: Grueneberg ganglion neurons. Blue: Nuclei.

  • ARG10794 anti-PDE2A antibody IHC-P image

    Immunohistochemistry: Paraffin-embedded Human ovarian medulla tissue stained with ARG10794 anti-PDE2A antibody at 1:1500 dilution.

  • ARG10794 anti-PDE2A antibody WB image

    Western blot: Recombinant PDE2A protein stained with ARG10794 anti-PDE2A antibody at 1:500 dilution.

Specific References

Electroacupuncture promotes the gastrointestinal motility of diabetic mice by CNP/NPR-B-cGMP and PDE3A-cGMP signaling.

WB / Mouse

An Jing et al.
Neurogastroenterol Motil.,  (2019)

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