ARG10807

anti-PDE7A antibody

anti-PDE7A antibody for ELISA,IHC-Formalin-fixed paraffin-embedded sections,Immunoprecipitation,Western blot,Dot blot and Human,Mouse,Rat

Overview

Product Description Rabbit Polyclonal antibody recognizes PDE7A
Tested Reactivity Hu, Ms, Rat
Tested Application Dot, ELISA, IHC-P, IP, WB
Host Rabbit
Clonality Polyclonal
Isotype IgG
Target Name PDE7A
Antigen Species Human
Immunogen Synthetic cyclic peptide common to all PDE7A variants.
Conjugation Un-conjugated
Full Name phosphodiesterase 7A
Alternate Names PDE7; High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A; EC 3.1.4.53; TM22; HCP1

Application Instructions

Application Suggestion
Tested Application Dilution
Dot1:10000
ELISA1:10000
IHC-PAssay-dependent
IP1:250
WB1:500
Application Note * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
Calculated MW 56 kDa

Properties

Form Liquid
Purification Affinity purified.
Buffer Tris-Glycine Buffer (pH 7.4 - 7.8), Hepes, 0.02% Sodium azide, 30% Glycerol and 0.5% BSA.
Preservative 0.02% Sodium azide
Stabilizer 30% Glycerol and 0.5% BSA
Concentration 0.5 mg/ml
Storage instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database links

GeneID: 18583 Mouse PDE7A

GeneID: 5150 Human PDE7A

Swiss-port # P70453 Mouse High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A

Swiss-port # Q13946 Human High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A

Gene Symbol PDE7A
Gene Full Name phosphodiesterase 7A
Background The protein encoded by this gene belongs to the cyclic nucleotide phosphodiesterase (PDE) family, and PDE7 subfamily. This PDE hydrolyzes the second messenger, cAMP, which is a regulator and mediator of a number of cellular responses to extracellular signals. Thus, by regulating the cellular concentration of cAMP, this protein plays a key role in many important physiological processes. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2011]
Function Hydrolyzes the second messenger cAMP, which is a key regulator of many important physiological processes. May have a role in muscle signal transduction. [UniProt]

Images (3) Click the Picture to Zoom In

  • ARG10807 anti-PDE7A antibody IHC-P image

    Immunohistochemistry: Paraffin-embedded Human ovarian medulla tissue stained with ARG10807 anti-PDE7A antibody at 1:200 dilution.

  • ARG10807 anti-PDE7A antibody WB image

    Western blot: 1) SKNMBE, 2) MCF7, 3) Human testis, and 4) Rat testis stained with ARG10807 anti-PDE7A antibody.

  • ARG10807 anti-PDE7A antibody WB image

    Western blot: 1) Lung, 2) Kidney, 3) Testis, 4) Pancreas, 5&7) Heart, and 6) Brain lysates stained with ARG10807 anti-PDE7A antibody at 1:500 dilution.