ARG46708

anti-PGC1 alpha antibody [AOBC-16]

anti-PGC1 alpha antibody [AOBC-16] for Western blot and Human,Mouse,Rat

Overview

Product Description Rabbit Monoclonal antibody [AOBC-16] recognizes PGC1 alpha
Tested Reactivity Hu, Ms, Rat
Tested Application WB
Host Rabbit
Clonality Monoclonal
Clone AOBC-16
Isotype IgG
Target Name PGC1 alpha
Antigen Species Human
Immunogen Synthetic peptide of human PGC1 alpha.
Conjugation Un-conjugated
Alternate Names PPARGC1A; PPARG Coactivator 1 Alpha; PGC1A; PGC1; PGC-1alpha; PPARGC1; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-Alpha; PPARgamma Coactivator 1alpha; PPARGC-1-Alpha; PGC-1-Alpha; LEM6; Peroxisome Proliferative Activated Receptor, Gamma, Coactivator 1, Alpha; Peroxisome Proliferator-Activated Receptor Gamma, Coactivator 1 Alpha; Peroxisome Proliferative Activated Receptor, Gamma, Coactivator 1; PPAR Gamma Coactivator Variant Form; PPAR-Gamma Coactivator 1-Alpha; Ligand Effect Modulator-6; Ligand Effect Modulator 6; PPARAGCIalpha; PGC-1(Alpha); L-PGC-1alpha; PPARAGCIα; PPARAGCIA; PGC-1v;

Application Instructions

Application Suggestion
Tested Application Dilution
WB1:500 - 1:2000
Application Note * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

Properties

Form Liquid
Purification Affinity chromatography purified
Buffer PBS, 150mM NaCl, 0.02% sodium azide, 50% glycerol and 0.4-0.5 mg/ml BSA.
Preservative 0.02% Sodium azide
Stabilizer 50% glycerol and 0.4-0.5 mg/ml BSA
Storage Instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links

GeneID: 10891 Human PPARGC1A

GeneID: 19017 Mouse PPARGC1A

GeneID: 83516 Rat PPARGC1A

Gene Symbol PPARGC1A
Gene Full Name PPARG Coactivator 1 Alpha
Background The protein encoded by this gene is a transcriptional coactivator that regulates the genes involved in energy metabolism. This protein interacts with PPARgamma, which permits the interaction of this protein with multiple transcription factors. This protein can interact with, and regulate the activities of, cAMP response element binding protein (CREB) and nuclear respiratory factors (NRFs). It provides a direct link between external physiological stimuli and the regulation of mitochondrial biogenesis, and is a major factor that regulates muscle fiber type determination. This protein may be also involved in controlling blood pressure, regulating cellular cholesterol homoeostasis, and the development of obesity. [provided by RefSeq, Jul 2008]
Function Transcriptional coactivator for steroid receptors and nuclear receptors. [UniProt]
Cellular Localization Cytoplasm; Nucleus. [UniProt]
Calculated MW 91 kDa
PTM Acetylation; Phosphoprotein; Ubl conjugation. [UniProt]

Images (3) Click the Picture to Zoom In

  • ARG46708 anti-PGC1 alpha antibody [AOBC-16] WB image

    Western blot: Hela stained with ARG46708 anti-PGC1 alpha antibody [AOBC-16].

  • ARG46708 anti-PGC1 alpha antibody [AOBC-16] WB image

    Western blot: Rat liver stained with ARG46708 anti-PGC1 alpha antibody [AOBC-16].

  • ARG46708 anti-PGC1 alpha antibody [AOBC-16] WB image

    Western blot: Mouse liver stained with ARG46708 anti-PGC1 alpha antibody [AOBC-16].