ARG67290
anti-RPA14 / RPA3 antibody
anti-RPA14 / RPA3 antibody for IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Mouse
Overview
| Product Description | Rabbit Polyclonal antibody recognizes RPA14 / RPA3 |
|---|---|
| Tested Reactivity | Hu, Ms |
| Tested Application | IHC-P, WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | RPA14 / RPA3 |
| Antigen Species | Human |
| Immunogen | Synthetic peptide corresponding to a.a. 30-80 of human RPA14 / RPA3. |
| Conjugation | Un-conjugated |
| Alternate Names | RPA3; Replication Protein A3; REPA3; RPA14; Replication Protein A 14 KDa Subunit; Replication Protein A3, 14kDa |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||
| Observed Size | 14 kDa |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity chromatography purified |
| Buffer | PBS, 0.02% sodium azide, 50% glycerol and 0.5% BSA |
| Preservative | 0.02% sodium azide |
| Stabilizer | 50% glycerol and 0.5% BSA |
| Concentration | 1 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links |
Swiss-port # P35244 Human Replication protein A 14 kDa subunit Swiss-port # Q9CQ71 Mouse Replication protein A 14 kDa subunit |
|---|---|
| Gene Symbol | RPA3 |
| Gene Full Name | Replication Protein A3 |
| Background | Enables damaged DNA binding activity and single-stranded DNA binding activity. Involved in DNA metabolic process. Part of DNA replication factor A complex. [provided by Alliance of Genome Resources, Jul 2025] |
| Function | As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. [UniProt] |
| Cellular Localization | Nucleus. [UniProt] |
| Calculated MW | 14 kDa |
| PTM | Acetylation; Isopeptide bond; Ubl conjugation. [UniProt] |
Images (2) Click the Picture to Zoom In
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ARG67290 anti-RPA14 / RPA3 antibody IHC-P image
Immunohistochemistry: Human oophoroma. 1 stained with ARG67290 anti-RPA14 / RPA3 antibody.
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ARG67290 anti-RPA14 / RPA3 antibody WB image
Western blot: MCF-7 stained with ARG67290 anti-RPA14 / RPA3 antibody.
