ARG45264
anti-SCO1 antibody
anti-SCO1 antibody for Flow cytometry,IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human
Overview
| Product Description | Polyclonal antibody recognizes SCO1 |
|---|---|
| Tested Reactivity | Hu |
| Tested Application | FACS, IHC-P, WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | SCO1 |
| Antigen Species | Human |
| Immunogen | Recombinant protein containing to human SCO1. |
| Conjugation | Un-conjugated |
| Alternate Names | SCO1; Synthesis Of Cytochrome C Oxidase 1; SCOD1; SCO1, Cytochrome C Oxidase Assembly Protein; SCO Cytochrome C Oxidase Assembly Protein 1; Protein SCO1 Homolog, Mitochondrial; SCO (Cytochrome Oxidase Deficient, Yeast) Homolog 1; SCO Cytochrome Oxidase Deficient Homolog 1 (Yeast); SCO Cytochrome Oxidase Deficient Homolog 1; MC4DN4 |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||||
| Observed Size | 30 kDa |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purification with immunogen. |
| Buffer | 0.2% Na2HPO4, 0.9% NaCl and 4% Trehalose. |
| Stabilizer | 4% Trehalose |
| Concentration | 0.5 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links |
Swiss-port # O75880 Human Protein SCO1 homolog, mitochondrial |
|---|---|
| Gene Symbol | SCO1 |
| Gene Full Name | Synthesis Of Cytochrome C Oxidase 1 |
| Background | Mammalian cytochrome c oxidase (COX) catalyzes the transfer of reducing equivalents from cytochrome c to molecular oxygen and pumps protons across the inner mitochondrial membrane. In yeast, 2 related COX assembly genes, SCO1 and SCO2 (synthesis of cytochrome c oxidase), enable subunits 1 and 2 to be incorporated into the holoprotein. This gene is the human homolog to the yeast SCO1 gene. [provided by RefSeq, Jul 2008] |
| Function | Copper metallochaperone essential for the maturation of cytochrome c oxidase subunit II (MT-CO2/COX2). Not required for the synthesis of MT-CO2/COX2 but plays a crucial role in stabilizing MT-CO2/COX2 during its subsequent maturation. Involved in transporting copper to the Cu(A) site on MT-CO2/COX2. [UniProt] |
| Cellular Localization | Membrane; Mitochondrion; Mitochondrion inner membrane. [UniProt] |
| Calculated MW | 34 kDa |
| PTM | Disulfide bond. [UniProt] |
Images (3) Click the Picture to Zoom In
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ARG45264 anti-SCO1 antibody IHC-P image
Immunohistochemistry: Human thyroid cancer stained with ARG45264 anti-SCO1 antibody at 2 μg/ml dilution.
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ARG45264 anti-SCO1 antibody WB image
Western blot: Daudi and 293T stained with ARG45264 anti-SCO1 antibody at 0.5 μg/ml dilution.
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ARG45264 anti-SCO1 antibody FACS image
Flow Cytometry: U87 stained with ARG45264 anti-SCO1 antibody at 1 µg/10^6 cells dilution.
