ARG10599

anti-SLC10A1 antibody

anti-SLC10A1 antibody for Western blot,IHC-Formalin-fixed paraffin-embedded sections and Human,Mouse,Rat

Overview

Product Description

Rabbit Polyclonal antibody recognizes SLC10A1

Tested Reactivity Hu, Ms, Rat
Tested Application IHC-P, WB
Host Rabbit
Clonality Polyclonal
Target Name SLC10A1
Antigen Species Human
Immunogen aa. 141-154 (YSRGIYDGDLKDKV) of Human SLC10A1.
Conjugation Un-conjugated
Full Name solute carrier family 10 (sodium/bile acid cotransporter), member 1
Alternate Names Sodium/bile acid cotransporter; Cell growth-inhibiting gene 29 protein; Na; Sodium/taurocholate cotransporting polypeptide; Solute carrier family 10 member 1; NTCP

Application Instructions

Application Suggestion
Tested Application Dilution
IHC-P0.5 - 1 µg/ml
WB0.5 - 1 µg/ml
Application Note Antigen Retrieval for IHC-P: steamed with pH 6 citrate buffer.

* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
Calculated MW 38~45 kDa

Properties

Form Liquid
Purification Affinity purification with immunogen.
Buffer PBS, 0.025% Sodium azide and 2.5% BSA.
Preservative 0.025% Sodium azide
Stabilizer 2.5% BSA
Concentration 0.5 mg/ml
Storage instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database links

GeneID: 20493 Mouse SLC10A1

GeneID: 24777 Rat SLC10A1

GeneID: 6554 Human SLC10A1

Gene Symbol SLC10A1
Gene Full Name solute carrier family 10 (sodium/bile acid cotransporter), member 1
Background The protein encoded by this gene belongs to the sodium/bile acid cotransporter family, which are integral membrane glycoproteins that participate in the enterohepatic circulation of bile acids. Two homologous transporters are involved in the reabsorption of bile acids; the ileal sodium/bile acid cotransporter with an apical cell localization that absorbs bile acids from the intestinal lumen, bile duct and kidney, and the liver-specific sodium/bile acid cotransporter, represented by this protein, that is found in the basolateral membranes of hepatocytes. Bile acids are the catabolic product of cholesterol metabolism, hence this protein is important for cholesterol homeostasis. [provided by RefSeq, Oct 2011]
Function The hepatic sodium/bile acid uptake system exhibits broad substrate specificity and transports various non-bile acid organic compounds as well. It is strictly dependent on the extracellular presence of sodium. [UniProt]

Images (2) Click the Picture to Zoom In

  • ARG10599 anti-SLC10A1 antibody IHC-P image

    Immunohistochemistry: Human liver cancer tissue stained with ARG10599 anti-SLC10A1 antibody.

  • ARG10599 anti-SLC10A1 antibody WB image

    Western blot: 1) Rat liver and 2) Rat brain lysate stained with ARG10599 anti-SLC10A1 antibody.