anti-SMO / Smoothened Homolog antibody

anti-SMO / Smoothened Homolog antibody for Western blot and Human


Product Description Rabbit Polyclonal antibody recognizes SMO / Smoothened Homolog
Tested Reactivity Hu
Tested Application WB
Host Rabbit
Clonality Polyclonal
Isotype IgG
Target Name SMO / Smoothened Homolog
Antigen Species Human
Immunogen Synthetic peptide of Human SMO / Smoothened Homolog.
Conjugation Un-conjugated
Alternate Names Gx; SMO; Protein Gx; Smoothened homolog; FZD11; SMOH

Application Instructions

Application Suggestion
Tested Application Dilution
WB5 - 10 µg/ml
Application Note * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
Positive Control Human brain.


Form Liquid
Purification Ammonium sulfate precipitation.
Buffer PBS and 0.08% Sodium azide.
Preservative 0.08% Sodium azide
Storage Instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.


Database Links

GeneID: 6608 Human SMO

Swiss-port # Q99835 Human Smoothened homolog

Gene Symbol SMO
Gene Full Name smoothened, frizzled class receptor
Background The protein encoded by this gene is a G protein-coupled receptor that interacts with the patched protein, a receptor for hedgehog proteins. The encoded protein tranduces signals to other proteins after activation by a hedgehog protein/patched protein complex. [provided by RefSeq, Jul 2010]
Function G protein-coupled receptor that probably associates with the patched protein (PTCH) to transduce the hedgehog's proteins signal. Binding of sonic hedgehog (SHH) to its receptor patched is thought to prevent normal inhibition by patched of smoothened (SMO). Required for the accumulation of KIF7 and GLI3 in the cilia. [UniProt]
Calculated MW 86 kDa

Images (1) Click the Picture to Zoom In

  • ARG22356 anti-SMO / Smoothened Homolog antibody WB image

    Western blot: 15 µg of Human brain lysate stained with ARG22356 anti-SMO / Smoothened Homolog antibody at 1) 10 µg/ml, and 2) 5 µg/ml dilution.