ARG45451
anti-ZO2 antibody
anti-ZO2 antibody for Flow cytometry,ICC/IF,IHC-Frozen sections,IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Mouse,Rat
Overview
| Product Description | Rabbit Polyclonal antibody recognizes ZO2 |
|---|---|
| Tested Reactivity | Hu, Ms, Rat |
| Tested Application | FACS, ICC/IF, IHC-Fr, IHC-P, WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | ZO2 |
| Antigen Species | Human |
| Immunogen | Synthetic peptide corresponding to C-terminal region of human ZO2. |
| Conjugation | Un-conjugated |
| Alternate Names | TJP2; X104; DFNA51; Tight junction protein ZO-2; C9DUPq21.11; Zonula occludens protein 2; ZO2; Zona occludens protein 2; PFIC4; DUP9q21.11; Tight junction protein 2 |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||||||||
| Observed Size | 60 kDa |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purified |
| Buffer | 0.9% NaCl, 0.2% Na2HPO4, 0.01% Sodium azide and 4% Trehalose. |
| Preservative | 0.01% Sodium azide |
| Stabilizer | 4% Trehalose |
| Concentration | 0.5 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Gene Symbol | TJP2 |
|---|---|
| Gene Full Name | tight junction protein 2 |
| Background | This gene encodes a zonula occluden that is a member of the membrane-associated guanylate kinase homolog family. The encoded protein functions as a component of the tight junction barrier in epithelial and endothelial cells and is necessary for proper assembly of tight junctions. Mutations in this gene have been identified in patients with hypercholanemia, and genomic duplication of a 270 kb region including this gene causes autosomal dominant deafness-51. Alternatively spliced transcripts encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Nov 2011] |
| Function | Plays a role in tight junctions and adherens junctions. [UniProt] |
| Cellular Localization | Cell junction; Cell membrane; Membrane; Nucleus; Tight junction. [UniProt] |
| Calculated MW | 134 kDa |
| PTM | Phosphoprotein. [UniProt] |
Images (6) Click the Picture to Zoom In
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ARG45451 anti-ZO2 antibody IHC-P image
Immunohistochemistry: Human intestinal cancer stained with ARG45451 anti-ZO2 antibody at 1 μg/ml dilution.
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ARG45451 anti-ZO2 antibody ICC/IF image
Immunofluorescence: A431 stained with ARG45451 anti-ZO2 antibody at 5 μg/ml dilution.
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ARG45451 anti-ZO2 antibody WB image
Western blot: RT4 and A431 stained with ARG45451 anti-ZO2 antibody at 0.5 μg/ml dilution.
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ARG45451 anti-ZO2 antibody FACS image
Flow Cytometry: MCF-7 stained with ARG45451 anti-ZO2 antibody at 1 µg/10^6 cells dilution.
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ARG45451 anti-ZO2 antibody WB image
Western blot: RH35 stained with ARG45451 anti-ZO2 antibody at 0.5 μg/ml dilution.
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ARG45451 anti-ZO2 antibody WB image
Western blot: Mouse liver stained with ARG45451 anti-ZO2 antibody at 0.5 μg/ml dilution.
