ARG10664

anti-Cathepsin B antibody

anti-Cathepsin B antibody for Western blot and Human

Overview

Product Description Rabbit Polyclonal antibody recognizes Cathepsin B
Tested Reactivity Hu
Tested Application WB
Host Rabbit
Clonality Polyclonal
Isotype IgG
Target Name Cathepsin B
Antigen Species Human
Immunogen Partial recombinant protein around aa. 80-333 of Human Cathepsin B.
Conjugation Un-conjugated
Full Name cathepsin B
Alternate Names EC 3.4.22.1; Cathepsin B; APPS; CPSB; APP secretase; Cathepsin B1

Application Instructions

Application Suggestion
Tested Application Dilution
WB1:500 - 1:2000
Application Note * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
Calculated MW ~ 38 kDa

Properties

Form Liquid
Purification Affinity purification with immunogen.
Buffer PBS, 0.025% Sodium azide and 2.5% BSA.
Preservative 0.025% Sodium azide
Stabilizer 2.5% BSA
Concentration 0.5 mg/ml
Storage instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database links

GeneID: 1508 Human CTSB

Swiss-port # P07858 Human Cathepsin B

Gene Symbol CTSB
Gene Full Name cathepsin B
Background The protein encoded by this gene is a lysosomal cysteine proteinase composed of a dimer of disulfide-linked heavy and light chains, both produced from a single protein precursor. It is also known as amyloid precursor protein secretase and is involved in the proteolytic processing of amyloid precursor protein (APP). Incomplete proteolytic processing of APP has been suggested to be a causative factor in Alzheimer disease, the most common cause of dementia. Overexpression of the encoded protein, which is a member of the peptidase C1 family, has been associated with esophageal adenocarcinoma and other tumors. At least five transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]
Function Thiol protease which is believed to participate in intracellular degradation and turnover of proteins. Has also been implicated in tumor invasion and metastasis. [UniProt]

Images (1) Click the Picture to Zoom In

  • ARG10664 anti-Cathepsin B antibody WB image

    Western blot: HepG2 cell lysate stained with ARG10664 anti-Cathepsin B antibody.