anti-Heme Oxygenase 1 antibody

anti-Heme Oxygenase 1 antibody for ICC/IF,IHC-Formalin-fixed paraffin-embedded sections,Immunoprecipitation,Western blot and Human,Mouse,Rat

publication_link Publication1


Product Description Rabbit Polyclonal antibody recognizes Heme Oxygenase 1
Tested Reactivity Hu, Ms, Rat
Tested Application ICC/IF, IHC-P, IP, WB
Host Rabbit
Clonality Polyclonal
Isotype IgG
Target Name Heme Oxygenase 1
Antigen Species Mouse
Immunogen Recombinant protein of Mouse Heme Oxygenase 1.
Conjugation Un-conjugated
Alternate Names bK286B10; Heme oxygenase 1; HO-1; EC; HMOX1D; HSP32

Application Instructions

Application Suggestion
Tested Application Dilution
Application Note * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
Positive Control A549
Observed Size ~ 33 kDa


Form Liquid
Purification Affinity purified.
Buffer 50 mM Tris-Glycine (pH 7.4), 150 mM NaCl, 0.01% Sodium azide, 40% Glycerol and 0.05% BSA.
Preservative 0.01% Sodium azide
Stabilizer 40% Glycerol and 0.05% BSA
Concentration Batch dependent
Storage Instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.


Database Links

GeneID: 15368 Mouse HMOX1

GeneID: 24451 Rat HMOX1

GeneID: 3162 Human HMOX1

Gene Symbol HMOX1
Gene Full Name heme oxygenase 1
Background Heme oxygenase, an essential enzyme in heme catabolism, cleaves heme to form biliverdin, which is subsequently converted to bilirubin by biliverdin reductase, and carbon monoxide, a putative neurotransmitter. Heme oxygenase activity is induced by its substrate heme and by various nonheme substances. Heme oxygenase occurs as 2 isozymes, an inducible heme oxygenase-1 and a constitutive heme oxygenase-2. HMOX1 and HMOX2 belong to the heme oxygenase family. [provided by RefSeq, Jul 2008]
Function Heme oxygenase cleaves the heme ring at the alpha methene bridge to form biliverdin. Biliverdin is subsequently converted to bilirubin by biliverdin reductase. Under physiological conditions, the activity of heme oxygenase is highest in the spleen, where senescent erythrocytes are sequestrated and destroyed. Exhibits cytoprotective effects since excess of free heme sensitizes cells to undergo apoptosis. [UniProt]
Cellular Localization Microsome. Endoplasmic reticulum membrane; Peripheral membrane protein; Cytoplasmic side. [UniProt]
Highlight Related Antibody Duos and Panels:
ARG30345 Keap1-Nrf2-ARE Antibody Panel
Related products:
Heme Oxygenase 1 antibodies; Heme Oxygenase 1 ELISA Kits; Heme Oxygenase 1 Duos / Panels; Anti-Rabbit IgG secondary antibodies;
Related news:
Keap1-Nrf2-ARE antibody panel is launched
Calculated MW 33 kDa

Images (2) Click the Picture to Zoom In

  • ARG43341 anti-Heme Oxygenase 1 antibody IHC-P image

    Immunohistochemistry: Paraffin-embedded Human lung cancer tissue stained with ARG43341 anti-Heme Oxygenase 1 antibody at 1:50 dilution.

  • ARG43341 anti-Heme Oxygenase 1 antibody WB image

    Western blot: A549 cell lysate stained with ARG43341 anti-Heme Oxygenase 1 antibody at 1:500 dilution.

Specific References

Identification of a novel immune-related gene signature for prognosis and the tumor microenvironment in patients with uveal melanoma combining single-cell and bulk sequencing data

WB / Human

Wanpeng Wang et al.
Front Immunol.,  (2023)