Keap1-Nrf2-ARE antibody panel is launched

Keap1-Nrf2-ARE antibody panel is launched




Transcription factor Nrf2 is a master regulator of the antioxidant responses. Nrf2 induces antioxidant gene expression by binding to the antioxidant response element (ARE). Most neurodegenerative disorders are characterized by oxidative stress. Nrf2 activation has a potential role in the treatment of neurodegeneration. Besides, Nrf2 is a therapeutic target in cancer as it protects cancer cells from oxidative damage. Nrf2 plays a critical role in mitigating lipid peroxidation and ferroptosis which is closely related to cancer and neurodegenerative diseases. Moreover, Nrf2 regulates inflammation processes via Nrf2/HO-1 axis and regulation of NLRP3 and AIM2 inflammasome and pyroptosis.

The newly launched Keap1-Nrf2-ARE antibody panel (ARG30345) is ideal for the research of Keap1-Nrf2-ARE pathway and HO-1 and NQO1 induction.  arigo offers more antibodies and panels to facilitate the research of crosstalk between Nrf2, ferroptosis, pyroptosis, and inflammation.


 

Keap1-Nrf2-ARE antibody panel (ARG30345)

- Includes IP-grade Nrf2 antibody
- Includes Nrf2 regulator Keap1 antibody
- Includes Nrf2 targets NQO1 and HO-1 antibodies
- Works on human and mouse samples

Component Reactivity Application Package
Keap1 antibody Hu, Ms, Rat IHC-P, WB 20 ul
Nrf2 antibody Hu, Ms ICC/IF, IHC-P, IP, WB 20 ul
NQO1 antibody Hu, Ms, Rat FACS, ICC/IF, IP, WB 20 ul
HO-1 antibody Hu, Ms, Rat FACS, ICC/IF, IP, WB 20 ul

 

 

● More antibodies and panels

Nrf2 activation Nrf2 pSer40 antibody (ARG40667)
Nrf2 degradation

Cullin 3 antibody (ARG58275)

RBX1 antibody (ARG55861)

Keap1 degradation Autophagy antibody panel (ARG30321)
Ferroptosis Ferroptosis/Oxytosis Antibody Panel (ARG30337)

Inflammasome &
Pyroptosis

Pyroptosis Antibody Panel (ARG30330)

NLRP3 Inflammasome Antibody Panel (ARG30331)

AIM2 antibody (ARG66617)

Inflammation

Inflammation antibody panel (ARG30323)

HMGB1 - total solution for research